Sort   by:  
 Page size 
TranscriptomicsRNAseq of naive CD4 T cells deficient for Elp3 activated for 18h against WT control
CD4 T cell deficient for the Elp3 gene have a delayed cell cycle entry. We explored by RNAseq by which molecular pathway the absence of Elp3 delayed the cell cycle entry. Naive T cell from CD4-cre Elp3 fl/fl mice and WT littermate were purified and activated in vitro with CD3 and CD28 antibodies for...
ORGANISM(S): Mus musculus 
2020-07-31 | E-MTAB-9057 | biostudies-arrayexpress
ProteomicsProteome of EPP2 cells with genetic deletion of Ctu1 or Elp3 and rapamycin treatment.
Proteome of the murine pancreatic cancer cell line EPP2 upon genetic deletion of Ctu1 or Elp3 and inhibition of mTORC1 with rapamycin.
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD047935 | Pride
Mtorc1 Elp3 Pancreatic cancer cells Ctu1 
TranscriptomicsRNAseq of follicular helper T cell from Elp3 deficient mice after Complete Freund Adjuvant immunisation
Loss of Elp3 in CD4 T cells hindered the development of an optimal T follicular helper T cell (TFH) response. To understand the molecular pathway by which Elp3 is necessary for TFH responses, mice deficient for Elp3 in T cells and WT littermate were immunized with ovalbumin emulsified with complete ...
ORGANISM(S): Mus musculus 
2020-07-31 | E-MTAB-9059 | biostudies-arrayexpress
ProteomicsThe proteomic of IL-4 treated BMDMs from Wt and Elp3 KO mice
This experiement aims to know what the differences of protein translation are in the bone marrow derived macro-phages(BMDMs) from WT mice and Elp3 KO mice. We treated the BMDMs with or without IL-4 for 4 hours.
ORGANISM(S): Mus musculus (Mouse) 
2022-09-12 | PXD033962 | Pride
M2 macrophages  il-4  elp3 
TranscriptomicsBT549 cells depleted of ELP3 compared to control
Understand the proteome dependent on the mcm5s2 U34 tRNA modification in breast cancer
ORGANISM(S): Homo sapiens 
2020-06-20 | E-MTAB-9206 | biostudies-arrayexpress
GenomicsRibosome profiling experiment in control or Elp3 depleted B16 melanoma cells
Ribosome profiling experiment in control or Elp3 depleted B16 melanoma cells
PRJNA438489 | ENA
TranscriptomicsRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Aim of the experiment was to compare the gene expression responses of long-term hematopoietic stem cells (HSCs) and myeloid-restricted progenitors (MyPs) to the hematopoietic cell-restricted deletion of the catalytic subunit Elp3 of the Elongator complex. Since Elp3 deletion resulted in activation o...
ORGANISM(S): Mus musculus 
2020-12-10 | E-MTAB-6992 | biostudies-arrayexpress
ProteomicsControl vs Elp3-deficient mouse myeloid progenitors 6-plex TMT LC-MSMS
6-plex TMT LC-MSMS quantification of proteins in myeloid progenitors (Lineage- Sca1- Kit+ cells) isolated from the bone marrow of 8-12 week old male and female control and Elp3-deficient (Elp3fl/fl vav-iCreT/+) mice. Biological triplicates of each genotype were analyzed, each consisting of 1.10e6 ce...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-26 | PXD010486 | Pride
Elongator Myeloid progenitor Elp3 Trna Hematopoiesis 
UnknownELP3 stabilizes c-Myc to promote tumorigenesis.
Not available
S-EPMC11054291 | biostudies-literature
TranscriptomicsPolysome profiling analysis of myeloid progenitors of control mice or mice conditionally deficient for Elp3 in the hematopoietic system
Aim of the experiment was to compare the genes enriched in the heavy polysome fraction of myeloid progenitors originating from control Elp3fl/fl mice, and in myeloid progenitors originating from mice that underwent hematopoietic cell-restricted deletion of the catalytic subunit Elp3 of the Elongator...
ORGANISM(S): Mus musculus 
2020-12-10 | E-MTAB-9628 | biostudies-arrayexpress
Sort   by:  
 Page size