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TranscriptomicsComparative genomic hybridization by array of human de novo actue myeloid leukemia (p-AML) samples and normal samples
Therapy-related acute myeloid leukemia (t-AML) is a severe complication of the cytotoxic therapy used for primary cancer treatment. The outcome of these patients is poor compared to people who develop de novo acute myeloid leukemia (p-AML). Chromosome abnormalities in t-AML are partly dependent on t...
ORGANISM(S): Homo sapiens 
2011-05-18 | E-TABM-1014 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human invasive and non-invasive non-functioning pituitary adenomas
Context : Non Functioning Pituitary Adenomas (NFPAs), although typically benign, may be locally invasive. Few datas are currently available related to the molecular process of invasion in sporadic pituitary adenomas. Markers of invasiveness, important for helping the clinician in the therapeutic s...
ORGANISM(S): Homo sapiens 
2010-03-18 | E-TABM-899 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization by array of human therapy related actue myeloid leukemia (t-AML) samples and normal samples
Therapy-related acute myeloid leukemia (t-AML) is a severe complication of the cytotoxic therapy used for primary cancer treatment. The outcome of these patients is poor compared to people who develop de novo acute myeloid leukemia (p-AML). Chromosome abnormalities in t-AML are partly dependent on t...
ORGANISM(S): Homo sapiens 
2011-06-08 | E-TABM-1015 | biostudies-arrayexpress
TranscriptomicsIGR_BREX_JF
The tissue stroma plays a major role in tumors natural history. Important programs for tumor progression such as epithelial mesenchymal transition are not activated as cell-autonomous processes but under the conditions of cross-talk between tumor and stroma. Adipose tissue is a major component of th...
ORGANISM(S): Homo sapiens 
2020-10-05 | E-MTAB-8638 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse C57Bl and nude strain xenografts from adherent and stem cells
Astrocytes may give raise to glioma, the most frequent primitive CNS tumours. TGFa, an EGF family member, is trophic for both astrocytes and gliomas cells and is frequently over-expressed in the early stages of glioma progression. Although its sole deregulation is insufficient to lead to cancerous t...
ORGANISM(S): Mus musculus 
2009-07-06 | E-TABM-706 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization by array of 121 paired tumor and non-tumor tissue samples from patients with non-small cell lung carcinoma to gain a systems biology insight into the current clinical classification
Non-small cell lung cancer (NSCLC), a leading cause of cancer deaths, represents a heterogeneous group of neoplasms, mostly comprising squamous cell carcinoma (SCC), adenocarcinoma (AC) and large-cell carcinoma (LCC). The aim of this study was to gain a systems biology insight into the current clini...
ORGANISM(S): Homo sapiens 
2013-12-11 | E-MTAB-1133 | biostudies-arrayexpress
TranscriptomicsIGR_CHORIOCARCINOMA_CGH_STUDY_HP
Not available
ORGANISM(S): Homo sapiens 
2011-02-14 | E-TABM-1117 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human malignant or benign breast cancer tumors to identify genes that present a differential expression between the two types of lesion
Background. Although gene expression arrays have been used to generate molecular predictors of relapse and drug sensitivity in breast cancer, no large study describes genes and exons differentially expressed between breast cancer and benign lesions.

Methods. One hundred and sixty-five tumour...
ORGANISM(S): Homo sapiens 
2009-12-30 | E-TABM-609 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human umbilical vein endothelial cells (HUVECs) transduced with pMLV-MCS or pMLV-THAP1 retroviral expression vectors
Goal of the experiment : Retroviral-mediated gene transfer of the THAP-zinc finger protein THAP1 inhibits endothelial cell proliferation through coordinated repression of critical cell cycle regulators and pRB-E2F target genes. Experimental design: To gain insight into the effects of THAP1 on endo...
ORGANISM(S): Homo sapiens 
2006-09-11 | E-TABM-24 | biostudies-arrayexpress
TranscriptomicsIGR_MITF_STUDY_BBRB
A recent study of the characteristics of coexisting melanoma and renal cell carcinoma RCC in the same patients supports a genetic predisposition underlying the association between these two cancers. The microphthalmia associated transcription factor (MITF) was proposed to act as a melanoma oncogene;...
ORGANISM(S): Homo sapiens 
2011-09-03 | E-TABM-1198 | biostudies-arrayexpress
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