Detoxification - OmicsDI

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Organisms

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Nostoc punctiforme PCC 73102 (2)
Mammalia (1)

Organisms

Mus musculus (106)
Homo sapiens (74)
Caenorhabditis elegans (26)
Lipomyces starkeyi (20)
Arabidopsis thaliana (20)
Rattus norvegicus (19)
Drosophila melanogaster (18)
Danio rerio (16)
Saccharomyces cerevisiae (14)
Spodoptera frugiperda (13)
Oryza sativa (13)
unidentified (11)
Lipomyces doorenjongii (10)
Escherichia coli (10)
Tetranychus urticae (9)
soil metagenome (9)
Lipomyces tetrasporus (6)
Folsomia candida (5)
Culex quinquefasciatus (5)
Bacillus subtilis (5)
Zea mays (5)
Lipomyces kononenkoae (4)
Hordeum vulgare (4)
Bactrocera dorsalis (4)
Aedes aegypti (4)
Apis mellifera (4)
Solanum lycopersicum (4)
Bos taurus (4)
Glycine max (4)
Chlamydomonas reinhardtii (4)

Repository

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pride (166)
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NODE (1)

Tissue

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Disease

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Acute myeloid leukemia (1)
Colorectal cancer liver metastases (1)
Colorectal Neoplasms (1)
Glycogen storage disease (1)
Kidney failure (1)
Campylobacteriosis (1)
Onchocerciasis (1)
Q fever (1)
Immune system (1)
Non-alcoholic steatohepatitis (1)
Hemolysis (1)
Non-alcoholic fatty liver (1)

Technology Type

Mass Spectrometry (166)
Shotgun proteomics (96)
Bottom-up proteomics (27)
Mass spectrometry assay (19)
Data-dependent acquisition (18)
Mass spectrometry (17)
Gel-based experiment (15)
Data-independent acquisition (11)
SWATH MS (8)
Top-down proteomics (5)
Affinity purification coupled with mass spectrometry proteomics (5)
HDMSE (3)
SRM/MRM (2)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
NMR spectroscopy (1)
Metaproteomics (1)
Proteogenomics (1)
Affinity proteomics (1)
All-ion fragmentation (1)

Instrument Platform

Illumina HiSeq 2000 (6)
NextSeq 500 (5)
Q Exactive (3)
Instrument (3)
Illumina Genome Analyzer II (2)
LTQ Orbitrap|1000449 (2)
Liquid Chromatography Tandem MS (LC-MS/MS) (2)
Agilent microarrays scanner G2565BA (1)
Agilent 2001 Bioanalyzer (1)
Nimblegen (1)
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Agilent G2505B (1)
DNA Microarray Scanner BA [Agilent Technologies] (1)
Axon- GenePix4000B (1)
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Illumina HiSeq 4000 (1)
Illumina MiSeq (1)
6530B Q-TOF LC/MS (1)
Q-Exactive HF mass spectrometer (1)
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Triple Quad 5500+, AB SCIEX (1)
6530A Q-TOF LC/MS (1)
LTQ XL (1)
TimsTOF Pro (1)

Publication Date

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2014 (77)
2015 (77)
2013 (75)
2010 (72)
2011 (65)
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2012 (59)
2008 (59)
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2020 (57)
2018 (56)
2016 (56)
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2019 (38)
2009 (38)
2007 (34)
2017 (32)
2006 (16)
2004 (10)
2005 (7)
2003 (1)

UNIPROT ID/AC

6PGL3_ORYSJ (2)
GSTU6_ORYSJ (2)
GSTF1_ORYSJ (2)
Q9LDC9_ORYSJ (2)
UGDH5_ORYSJ (2)
A0A0P0WU69_ORYSJ (2)
MAOC_ORYSJ (2)
Q2RBD1_ORYSJ (2)
UGDH4_ORYSJ (2)
Q7XSU7_ORYSJ (2)
A0A0P0W363_ORYSJ (2)
HSP82_ORYSJ (2)
A3A9W6_ORYSJ (2)
A0A0P0XTT3_ORYSJ (2)
Q67VM1_ORYSJ (2)
UGDH2_ORYSJ (2)
RL40B_ORYSJ (2)
Q9FTN6_ORYSJ (2)
A0A0P0XV80_ORYSJ (2)
Q8S702_ORYSJ (2)
Q8LNM7_ORYSJ (2)
A0A0P0VM80_ORYSJ (2)
A0A0P0X005_ORYSJ (2)
A0A0P0XLG1_ORYSJ (2)
A0A0P0X5U4_ORYSJ (2)
RL40A_ORYSJ (2)
Q06598 (1)
P39109 (1)
P23900 (1)
P32485 (1)

ENSEMBL ID

ENSG00000170477 (3)

CHEBI ID

CHEBI:17750 (3)
CHEBI:15428 (3)
CHEBI:16856 (2)
CHEBI:39548 (1)
CHEBI:29242 (1)
CHEBI:15356 (1)
CHEBI:17822 (1)
CHEBI:16811 (1)
CHEBI:63836 (1)
CHEBI:18237 (1)
CHEBI:1989 (1)
CHEBI:15611 (1)
CHEBI:15635 (1)
CHEBI:17515 (1)
CHEBI:27470 (1)
CHEBI:17724 (1)
CHEBI:36080 (1)
CHEBI:17858 (1)
CHEBI:16240 (1)
CHEBI:16680 (1)
CHEBI:18349 (1)
CHEBI:17230 (1)
CHEBI:15740 (1)
CHEBI:17622 (1)
CHEBI:18406 (1)
CHEBI:16842 (1)
CHEBI:15637 (1)
CHEBI:15641 (1)
CHEBI:15633 (1)
CHEBI:15414 (1)

Metabolite Name

Betaine (8)
Adenosine (8)
Hypoxanthine (7)
Creatinine (7)
Choline (7)
Uridine (7)
Trigonelline (6)
L-Tyrosine (6)
Ectoine (6)
Suberic acid (6)
L-Tryptophan (6)
Uracil (6)
Adenine (6)
Creatine (6)
Taurine (6)
L-Methionine (6)
Inosine (6)
Telmisartan (5)
Citric acid (5)
Malic acid (5)
Tryptophan (5)
Phenylalanine (5)
Glutaric acid (5)
Azelaic acid (5)
L-Histidine (5)
L-Phenylalanine (5)
Xanthine (5)
Sucrose (5)
Lys-Leu (4)
Ethephon (4)

First Public Date

2026 (217)
2025 (203)
2014 (161)
2024 (147)
2022 (95)
2023 (93)
2021 (85)
2020 (67)
2019 (58)
2018 (55)
2017 (46)
2015 (39)
2013 (31)
2016 (30)
2010 (1)

Modelling Approach

Ordinary differential equation model (4)

Study status

Recruiting (1)
Completed (1)

Lab affiliation

Department of Genome Sciences, University of Washington, Seattle (3)
School of Engineering, Westlake University (2)
Applied Proteomics Lab, Department of Biology, Maynooth University, Ireland. (2)
Department of Glycobiology, Institute of Chemistry, Slovak Academy of Sciences (2)
Department of Biochemistry, Microbiology and Immunology University of Ottawa, 451 Smyth Rd. Ottawa, Ontario, Canada, K1H 8M5 (1)
Director, Research Integrity and Compliance Review Office (http://ricro.colostate.edu/) Associate Professor, Mycobacteria Research Laboratories Dept of Microbiology, Immunology,& Pathology (http://www.cvmbs.colostate.edu/DirectorySearch/Search/MemberProfile/CVMBS/3607) Colorado State University Ft. Collins, CO 80523, USA (1)
ICAR-Central Inland Fisheries Research Institute, Barrackpore, Kolkata-700120, India (1)
Fruit and Tea Research Institute, Hubei Academy of Agricultural Sciences (1)
Bioanalytical Research Labs, Department of Biology, University of Salzburg, Austria (1)
State Key Laboratory of Marine Environmental Science / College of the Environment and Ecology, Xiamen University, China (1)
University of Oslo, Department of Biosciences, Oslo, Norway (1)
Department of Anatomy, Physiology, and Pharmacology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (1)
College of Life Sciences, Huaibei Normal University, Huaibei, Anhui 235000, P.R. China (1)
Department of Biochemistry, Microbiology and Immunology Institute of Systems Biology University of Ottawa (1)
Core Facility Proteomics Institute of Clinical Chemistry University Medical Center Göttingen (1)
Biomedical Research Center, Slovak Academy of Sciences (1)
Instituto de Hortofruticultura Subtropical y Mediterránea ‘‘La Mayora’’ –Departamento de Microbiología, Universidad de Málaga, Bulevar Louis Pasteur 31 (Campus Universitario de Teatinos), 29071 Málaga, Spain (1)
Fertility & Research Centre, School of Clinical Medicine, Faculty of Medicine & Health, University of New South Wales, Australia (1)
INstitute of Food Sciences- National Research Council of Italy (1)
Laboratory of Functional Proteomics (1)
Technische Universität Dresden Internationales Hochschulinstitut Zittau Juniorprofessur für Bioanorganische Chemie (1)
Laboratory of proteomic analysis, FSBIS SRI of Physical-Chemical Medicine FMBA of Russia (1)
Lab no. 54, Division of Genetics, ICAR-Indian Agricultural Research Institute (1)
Laboratorio de Metabolismo y Señalización en Plantas. Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET-UNR), Rosario, Argentina (1)
Departamento de Bioquímica y Biología Molecular. Edificio Severo Ochoa. Campus de Rabanales. Universidad de Córdoba. Córdoba, 14071. Spain (1)
Division of Biotechnology, MELISA Institute, Concepción, Chile. (1)
Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research - UFZ,Leipzig, Germany (1)
Department of Plant Bioscience, Pusan National University, Miryang, 50463, South Korea (1)
Department of Ecogenomics and Systems Biology, University of Vienna; Vienna Metabolomics Centre, University of Vienna, Austria (1)
Department of Infection Biology, Institute of Infection and Global Health, University of Liverpool. Liverpool, UK. (1)

Keyword

Zinc (1)
Zinc Sulfate (1)
Oxidative stress (1)

IsPrivate

False (5)

Model Flag

Non Kinetic (1)

Classification

bacteria (44)
fungi (12)
helminths (1)
protozoa (1)

Study type

Transcription profiling by array (282)
RNA-seq of coding RNA (57)
ChIP-seq (29)
ChIP-chip by tiling array (13)
Unknown experiment type (9)
ChIP-chip by array (7)
Methylation profiling by high throughput sequencing (5)
Methylation profiling by array (4)
Transcription profiling by tiling array (3)
Comparative genomic hybridization by array (3)
RNA-seq of non coding RNA (3)
Cell line - High-throughput sequencing (2)
Other (2)
Interventional (2)
FAIRE-seq (1)
MeDIP-seq (1)
Plant - One-color microarray (1)
RNAi profiling by array (1)
Genotyping by array (1)
Bisulfite-seq (1)
ATAC-seq (1)
DNA-seq (1)
RNA-seq of coding RNA from single cells (1)

Release Date

2022 (699)
2021 (644)
2025 (626)
2023 (571)
2024 (532)
2020 (481)
2019 (461)
2018 (419)
2015 (367)
2017 (367)
2016 (338)
2014 (301)
2013 (265)
2012 (213)
2010 (178)
2011 (159)
2008 (131)
2009 (128)
2026 (100)
2007 (69)
2005 (42)
2006 (36)
2004 (28)
2003 (20)
2001 (16)
2002 (14)
2000 (12)
1999 (7)
1998 (4)
1997 (3)

Location

Brazil (1)
China (1)

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Detoxification metabolic adaptation of Bombyx mori to artificial diet and functional study of key detoxification gene BmGSTd2

The exceptional adaptability of insects to diverse food sources is central to their survival and evolutionary success. However, the molecular mechanisms underlying this rapid adaptation remain largely uncharacterized. In this study, adaptive phenotypic, transcriptomic, and metabolomic differences...

2026-01-27 | MTBLS13782 | MetaboLights

Glycosylation-mediated detoxification of zearalenone by the Tibetan yeast Hannaella zeae: Multi-omics insights into its dual-function mechanism

This study investigated the detoxification of zearalenone (ZEN) by the Tibetan Plateau yeast Hannaella zeae via untargeted LC-MS/MS-based metabolomics. H. zeae was cultured in NYDB medium with ZEN supplementation, and samples were harvested after 36 h of incubation for metabolomic analysis. The c...

2026-08-20 | MTBLS15233 | MetaboLights

Unveiling superior phenol detoxification and degradation ability in Candida tropicalis SHC-03: A comparative study with Saccharomyces cerevisiae BY4742

This study examined the phenol degradation capabilities and oxidative stress responses of Candida tropicalis SHC-03, demonstrating its metabolic superiority and resilience compared to Saccharomyces cerevisiae BY4742 in a culture medium with phenol as the sole carbon source. Through comparative gr...

2024-10-04 | MTBLS10757 | MetaboLights

Talemi2014 - Arsenic toxicity and detoxification mechanisms in yeast

Talemi2014 - Arsenic toxicity and detoxification mechanisms in yeast The model implements arsenite (AsIII) transport regulation, its distribution within main cellular AsIII pools and detoxification. The intracellular As pools considered are free AsIII (AsIIIin), protein-bound AsIII (AsIIIprot), glut...

2024-09-02 | BIOMD0000000547 | BioModels

Transcription profiling of Aedes aegypti treated with permethrin to identify detoxification genes

Genomic analysis of detoxification genes in the mosquito Aedes aegypti.

ORGANISM(S): Aedes aegypti

2008-02-09 | E-TABM-413 | biostudies-arrayexpress

Transcriptional analysis of development and detoxification in Culex pipiens quinquefasciatus

The genomes of three major mosquito vectors of human diseases, including Anopheles gambiae, Aedes aegypti, and Culex pipiens quinquefasciatus, have been previously sequenced. C. p. quinquefasciatus has the largest number of predicted protein-coding genes, which partially results from the expansion o...

ORGANISM(S): Culex quinquefasciatus

2012-12-30 | E-GEOD-35744 | biostudies-arrayexpress

Transcription profiling of insecticide susceptible and resistant strains of Aedes aegypti to identify detoxification genes

Genomic analysis of detoxification genes in the mosquito Aedes aegypti

ORGANISM(S): Aedes aegypti

2008-02-09 | E-TABM-414 | biostudies-arrayexpress

Transcription profiling of Anopheles gambiae midgut and fat bodies 1 and 11 days post Plasmodium berghei infection to investigate responses in detoxification genes

Detoxification genes were assayed for their response to Plasmodium berghei infection at 1 and 11 days post infection in Anopheles gambiae mosquitoes.

ORGANISM(S): Anopheles gambiae

2010-08-11 | E-MTAB-195 | biostudies-arrayexpress

Manganese detoxification by Staphylococcus aureus

PRJNA511462 | ENA