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Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
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Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland
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xref:PubMed:41963349
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Proteomic analysis of nascent proteins in proximity to DFCP1 using SILAC labeling and APEX2-mediated biotin-streptavidin affinity purification.
This study employs a spatial proteomics approach combining APEX2 proximity labeling with SILAC (Stable Isotope Labeling by Amino acids in Cell culture) to map the nascent proteome in the vicinity of DFCP1.
ORGANISM(S):
Homo sapiens (Human)
2026-02-21
|
PXD073558
|
Pride
Proximity labeling
Autophagy
Apex2
Silac
Nascent proteins
Dfcp1
Cite
ATPase activity of DFCP1 controls selective autophagy.
Not available
S-EPMC10329651
|
biostudies-literature
Cite
DFCP1 is a regulator of starvation-driven ATGL-mediated lipid droplet lipolysis.
Not available
S-EPMC11721518
|
biostudies-literature
Cite
PI(3)P and DFCP1 regulate the biogenesis of lipid droplets.
Not available
S-EPMC9727793
|
biostudies-literature
Cite
The NTPase activity of the double FYVE domain-containing protein 1 regulates lipid droplet metabolism.
Not available
S-EPMC9881219
|
biostudies-literature
Cite
Early events in the generation of autophagosomes are required for the formation of membrane structures involved in hepatitis C virus genome replication.
Not available
S-EPMC5115167
|
biostudies-literature
Cite
Autophagy induced by calcium phosphate precipitates involves endoplasmic reticulum membranes in autophagosome biogenesis.
Not available
S-EPMC3528773
|
biostudies-literature
Cite
Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins.
Not available
S-EPMC3321844
|
biostudies-literature
Cite
A cluster of thin tubular structures mediates transformation of the endoplasmic reticulum to autophagic isolation membrane.
Not available
S-EPMC3993601
|
biostudies-literature
Cite
Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase.
Not available
S-EPMC3039730
|
biostudies-literature
Cite
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