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We have previously shown that standardized extracts of Ginkgo biloba (EGb) modulate fear memory formation, which is associated with CREB-1 (mRNA and protein) upregulation in the dorsal hippocampal formation (dHF), in a dose-dependent manner. Here, we employed proteomic analysis to investigate EGb ef...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-01-07 | PXD009894 | Pride
Background Deciphering host responses contributing to dengue shock syndrome (DSS), the life-threatening form of acute viral dengue infections, is required to improve both the differential prognosis and the treatments provided to DSS patients, a challenge for clinicians. Methodology/Principal Findin...
ORGANISM(S): Homo sapiens 
We investigated the abundances and transcriptomic changes of immune cells at several time points over the course of dengue virus infection. The PBMC samples were obtained from one dengue fever (DF) and one dengue hemorrhagic fever (DHF) patients (8 samples in total). The samples were harvested at tw...
ORGANISM(S): Homo sapiens 
Background: We report the detailed development of biomarkers to predict the clinical outcome under dengue infection. Transcriptional signatures from purified peripheral blood mononuclear cells were derived from whole-genome gene-expression microarray data and validated by quantitative PCR and tested...
ORGANISM(S): Homo sapiens 
Memory formation is an essential function for survival and cognitive flexibility that involves both synaptic and systems consolidation. The latter is an intricate process requiring integrated signalling inputs into complex neural networks over time. The purpose of the present study was to identify p...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-02-01 | PXD009876 | Pride
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