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UnknownA multicenter phase III prospective randomized trial of high-dose epirubicin in combination with cyclophosphamide (EC) versus docetaxel followed by EC in node-positive breast cancer. GOIM (Gruppo Oncologico Italia Meridionale) 9902 study.

Background

The Gruppo Oncologico Italia Meridionale 9902 trial compared four cycles of high-dose epirubicin plus cyclophosphamide (EC) with four cycles of docetaxel (Taxotere, D) followed by four cycles of EC as adjuvant treatment of node-positive breast cancer.

Patients and methods

P...
S-EPMC3362268 | biostudies-literature
TranscriptomicsProspective gene expression analysis of human RNA samples from Hepatocellular Carcinoma in relation with growth rate and survival
The aim of this study is to identify by whole genome microarray expression profiling a molecular signature of HCC samples that correlates with growth rate of the tumor and survival. This signature could eventually be used as prognostic marker. The samples were prospectively derived from hepatoce...
ORGANISM(S): Homo sapiens 
2014-01-22 | E-GEOD-54236 | biostudies-arrayexpress
TranscriptomicsmiR-10b*, a master inhibitor of the cell cycle, is downregulated in human breast tumors
Deciphering the molecular mechanisms involved in breast tumorigenesis has been the subject of extensive research in the last years; yet unpredictable response and development of resistance to adjuvant therapies remain major questions in the management of breast cancer patients. The power of miR expr...
ORGANISM(S): Homo sapiens 
2012-10-30 | E-GEOD-40525 | biostudies-arrayexpress
UnknownBeing the Family Caregiver of a Patient With Dementia During the Coronavirus Disease 2019 Lockdown.
Background: Family caregivers of patients with dementia are at high risk of stress and burden, and quarantine due to the coronavirus disease 2019 (COVID-19) pandemic may have increased the risk of psychological disturbances in this population. The current study was carried out during the nati...
S-EPMC8098661 | biostudies-literature
UnknownAssociation of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes.

Background

Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage ≥3 CKD has been less explored in type 1 diabetes me...
S-EPMC6280443 | biostudies-literature
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