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MetabolomicsLipid metabolites as potential diagnostic and prognostic biomarkers for acute community acquired pneumonia
Early diagnosis of acute community-acquired pneumonia (CAP) is important in patient triage and treatment decisions. To identify biomarkers that distinguish patients with CAP from non-CAP controls, we conducted an untargeted global metabolome analysis for plasma samples from142 patients with CAP (CAP...
2016-08-11 | MTBLS354 | MetaboLights
MetabolomicsNMR-based metabolic profiling provides diagnostic and prognostic information in critically ill children with suspected infection

Sepsis, defined as life-threatening organ dysfunction caused by infection is difficult to distinguish clinically from infection or post-operative inflammation. We hypothesized that in a heterogeneous group of critically ill children, there would be different metabolic profiles between post-operat...

2020-11-19 | MTBLS563 | MetaboLights
ProteomicsDiscrimination of Isomers of Released N- and O-Glycans Using Diagnostic Product Ions in Negative Ion PGC-LC-ESI-MS/MS
We used porous graphitized carbon-LC-ESI-MS/MS to separate and detect released N- and O-glycan isomers from mammalian model glycoproteins using negative mode resonance activation CID-MS/MS. By interrogating similar fragment spectra from closely related glycan isomers that differ only in arm position...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Homo Sapiens (ncbitaxon:9606) 
2019-04-15 | MSV000083688 | MassIVE
MetabolomicsIntegrated Multi-omics Analysis Identifies Diagnostic Biomarkers for Acute Coronary Syndrome in Type 2 Diabetes Mellitus Patients

Biomarkers for the early identification of acute coronary syndrome (ACS) risk remain inadequately investigated, particularly in patients with type 2 diabetes mellitus (T2DM), for whom timely clinical intervention may substantially enhance prognostic outcomes. The gut microbiota and serum metaboli...

2026-03-19 | MTBLS14087 | MetaboLights
TranscriptomicsTranscription profiling of human separated leukocyte subsets in SLE and vasculitis
Objective: To optimize a strategy for identifying gene expression signatures differentiating SLE and anti-neutrophil cytoplasmic antibody-associated vasculitis that provide insight into the pathogenesis and identify biomarkers.
Methods: Forty four vasculitis patients, 13 SLE patients and 25 age...
ORGANISM(S): Homo sapiens 
2010-06-02 | E-MTAB-145 | biostudies-arrayexpress
UnknownDiagnostic Model for Discrimination Between Tuberculous Meningitis and Bacterial Meningitis.
Not available
S-EPMC8632769 | biostudies-literature
UnknownWide complex tachycardia discrimination tool improves physicians' diagnostic accuracy.
Not available
S-EPMC9799284 | biostudies-literature
UnknownThe diagnostic discrimination of cutaneous α-synuclein deposition in Parkinson disease.
Not available
S-EPMC4970658 | biostudies-literature
UnknownAccurate discrimination of Hartnup disorder from other aminoacidurias using a diagnostic ratio.
Not available
S-EPMC6938934 | biostudies-literature
UnknownDiscrimination of benign, atypical, and malignant peripheral nerve sheath tumors in neurofibromatosis type 1 using diffusion-weighted MRI.
Not available
S-EPMC10926940 | biostudies-literature
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