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In order to study the gene expression profiles of monocyte and macrophages, we collected three type of cells and performed pair-wised comparison. It includes human peripheral blood monocyte (MONO), human peripheral blood monocyte derived macrophages treated with M-CSF (MACRO)and primary alveolar mac...
ORGANISM(S): Homo sapiens 
Polycomb repressive complex-2 (PRC2) is a histone methyltransferase required for epigenetic silencing during development and cancer. Long non-coding RNAs (lncRNAs) recruit PRC2 to chromatin, but the general role of RNA in maintaining repressed chromatin is unknown. ChIP-seq, combined with RNA-seq, i...
ORGANISM(S): Homo sapiens 
In lung diseases caused by the major mould pathogen Aspergillus fumigatus the pulmonary epithelium is destroyed by invasive growth of fungal hyphae, a process thought to require fungal proteases. Here we show that the A. fumigatus pH-responsive transcription factor PacC governs expression of secrete...
ORGANISM(S): Aspergillus fumigatus 
Transforming growth factor-M-NM-2 (TGF-M-NM-2) signalling controls a number of cerebral functions and dysfunctions including synaptogenesis, amyloid-M-NM-2 accumulation, apoptosis and excitotoxicity. Using cultured cortical neurons prepared from either wild type or transgenic mice over-expressing a ...
ORGANISM(S): Homo sapiens 
Data from ProteomeXchange, PXD ID: PXD000592. File: 130614_CornwallG_GB_GC3_HILIC.mzML. Published as part of Mol Cell Biol. 2014 May 5 . From the Abstract: {{i}} The acrosomal matrix (AM) is an insoluble structure within the sperm acrosome that serves as a scaffold controlling the release of AM ass...
ORGANISM(S): Abelson_murine_leukemia_virus_uid14654,ectromelia_virus_uid14211,minute_virus_of_mice_uid14019,moloney_murine_leukemia_virus_uid15030,moloney_murine_sarcoma_virus_uid14721,mouse_mammary_tumor_virus_uid14435,mouse_parvovirus_1_uid14325,mouse_parvovirus_2_uid17125,mouse_parvovirus_3_uid17123,mouse_parvovirus_4a_uid33009,mouse_parvovirus_5a_uid33007,murid_herpesvirus_1_uid15181,murid_herpesvirus_2_uid14419,murid_herpesvirus_4_uid14458,murine_adenovirus_3_uid37713,murine_adenovirus_a_uid14519,murine_hepatitis_virus_a59_uid15350,murine_hepatitis_virus_jhm_uid15138,murine_norovirus_1_uid17577,murine_osteosarcoma_virus_uid14655,murine_pneumotropic_virus_uid14071,murine_polyomavirus_uid15489,murine_type_c_retrovirus_uid15204, Mouse 
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