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TranscriptomicsEpigenetic events in early breast cancer
Subpopulations of primary Human Mammary Epithelial Cells (HMEC) have the unique ability to escape a period of growth arrest and continue to proliferate. These cells, called post-selection or variant cells (vHMEC), share features with premalignant breast cancer lesions, including p16INK4A promoter h...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-8007 | biostudies-arrayexpress
TranscriptomicsEffect of 3,OC12-HSL on the transcriptome of the ectomycorrhizal fungus Laccaria bicolor S238N
Bacteria use small diffusible molecules to communicate and to coordinate population response by a cell density-depend mechanism named quorum sensing (QS). If such a cross-talk was first described between bacterial species, it was recently evidenced that bacterial QS signal molecules can also be sen...
ORGANISM(S): Laccaria bicolor S238N-H82 
2010-11-23 | E-GEOD-18635 | biostudies-arrayexpress
TranscriptomicsDiscovery of candidate genes and pathways in the endometrium regulating ovine blastocyst growth and conceptus elongation
Establishment of pregnancy in ruminants requires blastocyst growth to form an elongated conceptus that produces interferon tau, the pregnancy recognition signal, and initiates implantation. Blastocyst growth and development requires secretions from the uterine endometrium. An early increase in circu...
ORGANISM(S): Ovis aries 
2010-05-15 | E-GEOD-17401 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of upper beak primorida of five species of Darwins Finches to identify species and/or size specific transcripts
We used five different species of Darwin’s Finches (G. magnirostris, G. conirostris, G. fortis, G. scandens, G. difficilis). G. difficilis was used as a common reference and we polled RNA from 9 unrelated individuals of this species to lower variation. We used at least two unrelated individual embr...
ORGANISM(S): Geospiza magnirostris 
2022-11-21 | E-MEXP-702 | biostudies-arrayexpress
TranscriptomicsGene expression in clonogenic versus non-clonogenic in pooled early passage OCI/AML-4 single cells
Identification of genes that regulate clonogenicity of AML cells is hindered by the difficulty of isolating pure populations of cells with defined proliferative abilities. Using early passages of the OCI/AML-4 cell line we sought to determine genes differentially expressed between clonogenic and no...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-28612 | biostudies-arrayexpress
ProteomicsComparison of Drosophila melanogaster adult and embryo proteome
Embryo and adult flies infected with Wolbachia pipientis or cured were lysed in a SDS containing buffer and digested with trypsin using in gel digestion. The resulting peptides were injected on a Sciex Triple-TOF 6600 in SWATH-MS mode. The data were analysed using Spectronaut 10 using the spectral l...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2018-08-10 | MSV000082812 | MassIVE
TranscriptomicsTranscription profiling of human grade 3 invasive ductal carcinomas vs. a common reference differentiates distinct subtypes of grade 3 invasive ductal carcinoma
Comparison of multiple grade 3 invasive ductal carcinomas arrayed against a common reference.
ORGANISM(S): Homo sapiens 
2007-06-01 | E-MEXP-1007 | biostudies-arrayexpress
TranscriptomicsDifferences in major bacterial taxa in three high Arctic soils lead to different CO2 production rates
The melting of permafrost and its potential impact on greenhouse gas emissions is a major concern in the context of global warming. The fate of the carbon trapped in permafrost will largely depend on soil physico-chemical characteristics, among which are the quality and quantity of organic matter, p...
ORGANISM(S): environmental samples 
2011-01-01 | E-GEOD-24800 | biostudies-arrayexpress
TranscriptomicsGene expression profile of a murin neuroblastoma cell line infected with the prion strain 22L
The underlying pathogenic mechanisms of prion infection are not well characterized. To study the effect of prion infection on gene expression in neuronal cell cultures, a neuroblastoma (N2a) cell clone was infected with either the mouse adapted prion strain 22L or exposed to uninfected brain homogen...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-7119 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Porphyromonas gingivalis wild type and mutant PG1432::ermF to identify genes which have their expression influenced by PG1432
The aim of this experiment is to ascertain which genes have their expression influenced by PG1432. PG1432 encodes a putative sensor histidine kinase which is part of two component signal transduction that was highly up-regulated in P. gingivalis mature biofilm cells. PG1432 was disrupted in P. gingi...
ORGANISM(S): Porphyromonas gingivalis 
2010-01-11 | E-TABM-546 | biostudies-arrayexpress
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