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TranscriptomicsSmall nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia
Small nucleolar RNAs (snoRNAs) and small Cajal body-specific RNAs are non-coding RNAs involved in the maturation of other RNA molecules. Alterations of sno/scaRNA expression may play a role in cancerogenesis. This study elucidates the patterns of sno/scaRNA expression in highly purified cells from 2...
ORGANISM(S): Homo sapiens 
2014-03-24 | E-GEOD-46261 | biostudies-arrayexpress
TranscriptomicsGenomic profiles for human peripheral blood T cells, B cells, natural killer cells, monocytes, and polymorphonuclear cells: comparisons to ischemic stroke, migraine, and Tourette syndrome
Blood genomic profiling has been applied to disorders of the blood and various organ systems including brain to elucidate disease mechanisms and identify surrogate disease markers. Since most studies have not examined specific cell types, we performed a preliminary genomic survey of major blood cell...
ORGANISM(S): Homo sapiens 
2015-09-03 | E-GEOD-72642 | biostudies-arrayexpress
TranscriptomicsExpression analysis of common myeloid progenitors (CMPs) expressing Hes1
High levels of Hes1 expression are frequently found in BCR-ABL-positive chronic myelogenous leukemia in blast crisis (CML-BC). In mouse bone marrow transplantation (BMT) models, co-expression of BCR-ABL and Hes1 induces CML-BC–like disease; however the underlying mechanism remained elusive. Here, ba...
ORGANISM(S): Mus musculus 
2014-05-01 | E-GEOD-56921 | biostudies-arrayexpress
UnknownNm-Mut-seq: a base-resolution quantitative method for mapping transcriptome-wide 2'-O-methylation.
Not available
S-EPMC10474006 | biostudies-literature
UnknownInnate Conformational Dynamics Drive Binding Specificity in Anti-Apoptotic Proteins Mcl-1 and Bcl-2.
Not available
S-EPMC10249625 | biostudies-literature
UnknownBlood culture practices and microbiological capacity for sepsis diagnostics in Europe (2021-2022): a cross-sectional analysis of the European Sepsis Care Survey.
Not available
S-EPMC12771334 | biostudies-literature
UnknownEvaluation of a digital remote extraction analysis and monitoring tool for key performance indicators (KPIs) in the blood culture process.
Not available
S-EPMC12619790 | biostudies-literature
TranscriptomicsCGH analysis of human colorectal carcinoma HCT116 cells that escaped from entescence
The engulfment of live cells by other live cells, also known as cannibalism, can result in the death of engulfed cells. Recently, we show that autophagy favors the accumulation of E-cadherins on the surface of cannibal cells, thereby enhancing their capacity to engulf and eliminate live cells. Impor...
ORGANISM(S): Homo sapiens 
2019-01-01 | E-MTAB-6802 | biostudies-arrayexpress
TranscriptomicsDifferential in vivo tumorigenicity of distinct subpopulations from a luminal-like breast cancer model (expression)
The cellular heterogeneity of one patient derived orthotopic breast cancer xenograft model (PDBCX) was investigated using flow cytometry , combined with assessment of in vivo tumorigenicity and whole genome expression profiling. Epithelial cell adhesion molecule (EpCAM) was revealed as a highly spec...
ORGANISM(S): Homo sapiens 
2015-05-26 | E-GEOD-48384 | biostudies-arrayexpress
UnknownTrypanosoma brucei Acyl-Protein Thioesterase-like (TbAPT-L) Is a Lipase with Esterase Activity for Short and Medium-Chain Fatty Acids but Has No Depalmitoylation Activity.
Not available
S-EPMC9693859 | biostudies-literature
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