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no omics definedTranscription profiling of mouse 6780 cell line derived from murine T-cell lymphomaTGFbeta dependent gene expression in T-cell lymphomas
The cell line "6780" derived from murine T-cell lymphoma was grown in RPMI medium 1640 with 10% FBS/1% penicillin/Streptomycin/1% l-glutamine/50 μM 2-mercaptoethanol. Vector constructs containing a dominant negative mutant of the human TGF-beta receptor type II (pMSCV-TGFBR-IRES-GFP) or an empty ve...
ORGANISM(S): Mus musculus 
2010-01-01 | E-MEXP-2233 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human healthy subjects, patients with Crohns Disease, and patients with Ulcerative Colitis to compare PBMCs in inflammatory bowel disease
Comparison of PBMC transcriptional profiles in healthy subjects, patients with Crohn's Disease, and patients with Ulcerative Colitis
ORGANISM(S): Homo sapiens 
2007-09-07 | E-GEOD-3365 | biostudies-arrayexpress
Transcriptomicssingle-cell RNA-seq of of dermal fibroblasts
Dermal fibroblasts from human, rhesus macaque, mouse and rat, stimulated with dsRNA (poly I:C) in a time course of 0,2,4 and 8 hours, profiled using the Smart-seq2 protocol.
The innate immune response - the expression programme that is initiated once a pathogen is sensed - is known to be variable...
ORGANISM(S): Macaca mulatta 
2018-07-06 | E-MTAB-5920 | biostudies-arrayexpress
MetabolomicsTGF-β uncouples glycolysis and inflammation in macrophages and controls the survival during sepsis

The mechanisms by which macrophage metabolism is regulated and the effects of metabolism on diseases remain largely unknown. We show here that TGF-β regulates the glycolysis of macrophages independently of inflammatory cytokine production, and thus affects the survival in experimental sepsis. Spe...

2023-02-17 | MTBLS6886 | MetaboLights
TranscriptomicsTranscriptional profiling using microarrays to elucidate the effects of partial whiB1 gene deletion in Mycobacterium tuberculosis H37Rv
DNA microarray analysis was performed on RNA from a strain of Mycobacterium tuberculosis H37Rv in which the essential whiB1 gene was deleted from the chromosome but partially complemented by a wild type allele on a plasmid, compared to RNA from H37Rv wild type containing the same plasmid.
ORGANISM(S): Mycobacterium tuberculosis 
2017-12-22 | E-MTAB-5814 | biostudies-arrayexpress
UnknownComposite measures of motor performance and self-efficacy are better determinants of postural instability and gait difficulties than individual clinical measures in Parkinson's disease.
Not available
S-EPMC10028594 | biostudies-literature
TranscriptomicsAnalysis of the coding exome of follicular lymphoma
Follicular lymphoma (FL) constitutes the second most common non-Hodgkin lymphoma in the Western world. FL carries characteristic recurrent structural genomic aberrations. However, information regarding the coding genome in FL is still evolving. Here, we describe the results of massively parallel ex...
ORGANISM(S): Homo sapiens 
2014-01-17 | E-GEOD-50973 | biostudies-arrayexpress
ProteomicsA proteomics-based method for identifying antigens within immune complexes
A novel approach to recover and identify immune complexes (ICs) was developed using size exclusion chromatography (SEC) and affinity chromatography on immunoglobulin binding columns (HiTrap Protein G). The purification process was monitored by 1D SDS-PAGE, protein staining, Western blotting and, fin...
ORGANISM(S): Betainfluenzavirus Homo sapiens (Human) Alphainfluenzavirus 
2021-01-04 | PXD021575 | Pride
Influenza Immune complexes Human Metaproteomics Orbitrap 
UnknownMachine learning for prediction of all-cause mortality in patients with suspected coronary artery disease: a 5-year multicentre prospective registry analysis.
Not available
S-EPMC5897836 | biostudies-literature
TranscriptomicsSingle-cell RNA-sequencing resolves a CD4+ T cell fate bifurcation
Single-cell RNA sequencing (scRNA-seq) was used to study the various transcriptional states of individual CD4+ T cells during blood-stage Plasmodium chabaudi infection in mice. This is an experimental model of malaria in which CD4+ T cells are essential for controlling parasite numbers, and which is...
ORGANISM(S): Mus musculus 
2017-03-21 | E-MTAB-4388 | biostudies-arrayexpress
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