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ProteomicsExploring the molecular mechanism of dihydroartemisinin regulating spleen immunity based on proteomics and phosphoproteomic
The molecular mechanisms through which dihydroartemisinin (DHA) induces immunomodulation in vivo remain unclear. Herein, DHA-regulated proteins and their phosphorylation profiles were identified and characterized, in the spleens of mice, using proteomics and phosphoproteomic approaches. We found tha...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-29 | PXD030353 | Pride
Dihydroartemisinin Phosphoproteomic Proteomics Immunomodulatory activity 
GenomicsAnti-fibrosis effects of dihydroartemisinin on primary skin fibroblast from healthy people
Anti-fibrosis effects of dihydroartemisinin on primary skin fibroblast from healthy people
PRJNA682197 | ENA
GenomicsDihydroartemisinin sensitizes cancer cells to ferroptosis in multiple myeloma
Dihydroartemisinin sensitizes cancer cells to ferroptosis in multiple myeloma
PRJNA977961 | ENA
TranscriptomicsMolecular dynamics and experimental verification studies of the mechanism of dihydroartemisinin in the treatment of colorectal cancer
SW480 cells were used to study the mechanism of dihydroartemisinin in the treatment of colorectal cancer. The cells in the experimental group were treated with 20 μg/ml dihydroartemisinin, and the control group was treated with culture medium containing 0.1% DMSO. The experimental group and the cont...
ORGANISM(S): Homo sapiens 
2022-09-26 | GSE214030 | GEO
TranscriptomicsApplication of a Agilent hydatid 4x44k - cDNA microarray for identification of dihydroartemisinin targeting genes in Echinococcus granulosus larval protoscoleces
A cDNA microarray composed of 9306 uniEST probes was constructed andapplied to detect the gene expression profile of protoscoleces of E. granulosus treated with dihydroartemisinin in vitro, respectively. Compared with the untreated protoscoleces, 752 genes were up-regulated and 269 genes were down-r...
ORGANISM(S): Echinococcus granulosus 
2021-09-29 | GSE184908 | GEO
GenomicsApplication of a Agilent hydatid 4x44k - cDNA microarray for identification of dihydroartemisinin targeting genes in Echinococcus granulosus larval protoscoleces
Application of a Agilent hydatid 4x44k - cDNA microarray for identification of dihydroartemisinin targeting genes in Echinococcus granulosus larval protoscoleces
PRJNA767013 | ENA
TranscriptomicsPlasmodium parasites mount an arrest response against dihydroartemisinin [Microarray]
Control of malaria is threatened by emerging parasite resistance to artemisinin drug (ART) therapies. The molecular details of how Plasmodium malaria parasites response to ART and how this relates to resistance is not clear. To determine how parasites respond to ART by altering gene expression, we p...
ORGANISM(S): Plasmodium falciparum 
2015-10-15 | E-GEOD-61536 | biostudies-arrayexpress
UnknownDihydroartemisinin-Piperaquine for the Prevention of Malaria in Pregnancy.
Not available
S-EPMC4847718 | biostudies-literature
TranscriptomicsAnti-fibrosis effects of dihydroartemisinin on primary skin fibroblast from healthy people
The objective of this study was to determine whether Dihydroartemisinin (DHA), a drug highly effective in treating malaria infection with good safety, could be repurposed for the treatment of skin fibrosis in systemic sclerosis (SSc). mRNA-seq of primary human fibroblast cultures from healthy donors...
ORGANISM(S): Homo sapiens 
2020-12-03 | GSE162550 | GEO
GenomicsDihydroartemisinin inhibits the proliferation of multiple myeloma cancer stem cells via disturbing nuclear lamina and chromatin architecture
Dihydroartemisinin inhibits the proliferation of multiple myeloma cancer stem cells via disturbing nuclear lamina and chromatin architecture
PRJNA667951 | ENA
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