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ProteomicsComparing SILAC- and stable isotope dimethyl-labeling approaches for quantitative proteomics.
Comparison of SILAC and reductive dimethyl labeling; also applied both methods to affinity enrichment experiments with and without fractionation.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-29 | MSV000082868 | MassIVE
ProteomicsDimethyl labeling-based quantitative PTM proteomic analysis of drought-regulated phosphoproteomes in soybean drought-tolerant cultivar
The isotopic dimethyl labeling-based quantitative post-translational modification proteomics was applied to study the phosphoproteomic changes associated with the drought responses of two contrasting soybean cultivars. A total of 9,457 non-redundant, unambiguous, label-independent and repeatable pho...
ORGANISM(S): Glycine max 
2023-05-10 | PXD022806 | Pride
Dimethyl labelling Quantitative ptm proteomics Orbitrap fusion lumos Phosphoproteomics Glycine max Overly post-translationally modified protein (opp) Soybean drought-tolerant cultivar 
ProteomicsDimethyl labeling-based quantitative PTM proteomic analysis of drought-regulated phosphoproteomes in soybean drought-tolerant cultivar
The isotopic dimethyl labeling-based quantitative post-translational modification proteomics was applied to study the phosphoproteomic changes associated with the drought responses of two contrasting soybean cultivars. A total of 9,457 non-redundant, unambiguous, label-independent and repeatable pho...
ORGANISM(S): Glycine max 
2021-09-09 | PXD022794 | Pride
Dimethyl labelling Quantitative ptm proteomics Orbitrap fusion lumos Phosphoproteomics Glycine max Overly post-translationally modified protein (opp) Soybean drought-tolerant cultivar 
UnknownEstablishment of Dimethyl Labeling-based Quantitative Acetylproteomics in Arabidopsis.
Not available
S-EPMC5930405 | biostudies-literature
UnknownIn-depth qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immunoaffinity purification and stable isotope dimethyl labeling.
Not available
S-EPMC2808269 | biostudies-literature
ProteomicsNano-liquid chromatography-orbitrap MS/MS-based quantitative proteomics reveals differences between the mechanisms of action of carnosic acid and carnosol in colon cancer cells
A shotgun proteomics study based on stable isotope dimethyl labeling (DML) and nano liquid chromatography-tandem mass spectrometry (nano-LC-MS/MS) has been performed to identify the relative changes in proteins and to gain some light on the specific molecular targets and mechanisms of action of CA a...
ORGANISM(S): Homo sapiens (Human) 
2016-12-23 | PXD004253 | Pride
Carnosol Mass spectrometry Colon cancer Dimethyl labeling Carnosic acid 16 foodomics Ht-29 cells Quantitative proteomics Antiproliferative activity 
ProteomicsLarge scale qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immuno-affinity purification and stable isotope dimethyl labeling
Triplex stable isotope dimethyl labeling of phosphotyrosine peptides after EGF stimulation
ORGANISM(S): Homo sapiens (Human) 
2010-07-09 | PRD000123 | Pride
ProteomicsA specific Kinase-substrate Regulation Network upon κ-opioid Receptor Activation
Kappa Opioid receptors（KORs） belong to family A of G-protein–coupled receptors (GPCRs), and the involvement of their ligands in analgesia and sedation has been extensively studied. KORs, which are expressed in the central and peripheral nervous systems are well known to exert potent anti-nociceptive...
ORGANISM(S): Homo sapiens (Human) 
2022-02-23 | PXD008349 | Pride
Phosphoproteome Dimethyl labeling Κ-opioid receptor 
ProteomicsEstablishment of dimethyl labeling-based quantitative acetylproteomics in Arabidopsis
Protein acetylation, one of many types of post-translational modifications (PTMs), is involved in a variety of biological and cellular processes. In the present study, we applied both CsCl density gradient (CDG) centrifugation-based protein fractionation and a dimethyl-labelling-based 4C quantitativ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-03-14 | PXD006177 | Pride
Cscl density gradient (cdg) centrifugation Stable isotope dimethyl labelling Arabidopsis Squa-d Acetylproteomics 4c proteomic workflow Quantitative ptm proteomics 
UnknownOnco-proteogenomics identifies urinary S100A9 and GRN as potential combinatorial biomarkers for early diagnosis of hepatocellular carcinoma.
Not available
S-EPMC4669941 | biostudies-literature
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