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ProteomicsThe quantitative proteomes of human-induced pluripotent stem cells and embryonic stem cells
Assessing relevant molecular differences between human-induced pluripotent stem cells (hiPSCs) and human embryonic stem cells (hESCs) is important, given that such differences may impact their potential therapeutic use. Controversy surrounds recent gene expression studies comparing hiPSCs and hESCs....
ORGANISM(S): Homo sapiens (Human) 
2013-02-01 | PXD000134 | Pride
Lc-msms Embryonic stem cells Reprogramming Fibroblast Etd Ips cells 
GenomicsDual roles of RNF2 in melanoma progression [ChIP-seq]
Epigenetic regulators have emerged as critical factors governing the biology of cancer. Here, in the context of melanoma, we show that RNF2 is prognostic, exhibiting progression-correlated expression in human melanocytic neoplasms. Through a series of gain of function and loss of function studies, w...
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-51929 | biostudies-arrayexpress
TranscriptomicsRnf41 is associated with anxiety like behavior, major depression and beta carboline induced seizure
The molecular etiology of invididual differences in complex behavior traits and susceptibility to psychiatric illness remains incomplete. Using an unbiased genetic approach in a mouse model, Quantitative Trait Loci (QTL) influencing anxiety-like behaviors and beta-carboline-induced seizure vulnerabi...
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-8641 | biostudies-arrayexpress
UnknownAdherens junction proteins in the hamster uterus: their contributions to the success of implantation.
Not available
S-EPMC3197917 | biostudies-literature
UnknownFrom genome to drug lead: identification of a small-molecule inhibitor of the SARS virus.
Not available
S-EPMC7119130 | biostudies-literature
TranscriptomicsQuantitative time-course profiling of Plasmodium falciparum transcripts and proteins throughout the 48-hour intraerythrocytic developmental cycle
Quantitative studies of the P. falciparum transcriptome have shown that the tightly controlled progression of the parasite through the intraerythrocytic developmental cycle (IDC) is accompanied by a continuous gene expression cascade where most expressed genes exhibit a single transcriptional peak. ...
ORGANISM(S): Plasmodium falciparum 
2011-06-07 | E-GEOD-24416 | biostudies-arrayexpress
UnknownStructures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase.
Not available
S-EPMC9481577 | biostudies-literature
UnknownInhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction.
Not available
S-EPMC4062832 | biostudies-literature
Proteomics,MultiomicsIMR90_iPS_BioReplica_02_ETD
Hs iPS_vs_HES - IMR90_iPS_BioReplica_02 ETD
ORGANISM(S): Homo Sapiens (human) 
2011-12-31 | PAe004086 | PeptideAtlas
Proteomics,MultiomicsIMR90_iPS_BioReplica_01_ETD
Hs iPS_vs_HES - IMR90_iPS_BioReplica_01 ETD
ORGANISM(S): Homo Sapiens (human) 
2011-12-31 | PAe004072 | PeptideAtlas
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