Sort   by:  
 Page size 
ProteomicsEffect of LPS and the glucocorticoid dexamethasone on the mouse Bone Marrow Derived Macrophage Proteome
The concentrations and copy number of proteins in the mouse Bone Marrow Derived proteome was determined for control, 10 ng/mL LPS stimulation, and LPS stimulation plus the addition of 100 nM dexamethasone, after an incubation for 24 hours and with four biological replicates for each condition. Over ...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD041375 | Pride
Innate immunity Glucocorticoid Macrophage Dexamethasone Mouse Type i interferon 
ProteomicsGenetic and pharmacologic inhibition of Keap1 dampens the pro-fibrotic program in human hepatic stellate cells
The increasing prevalence of chronic liver diseases (CLDs) is a global health concern. CLDs can cause fibrosis, and there is an urgent need for antifibrotic agents. The primary driver of fibrogenesis, transforming growth factor beta 1 (TGF-β1), activates hepatic stellate cells (HSCs), which are resp...
ORGANISM(S): Homo sapiens (Human) 
2026-09-24 | PXD076470 | Pride
Ecm Fibrosis Liver Nrf2 Anti-fibrotic drugs Antioxidant response 
Sort   by:  
 Page size