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ProteomicsAutoimmunity-associated DIORA1 binds the MRCK family of serine/threonine kinases and controls cell motility
Genetic association links DIORA1 to numerous autoimmune rheumatic diseases including systemic lupus erythematous, Sjögren's disease, myositis, scleroderma and rheumatoid arthritis, but its cellular function remains unknown. Here, we identify the MRCK kinase family as DIORA1 interactors. MRCK kinases...
ORGANISM(S): Homo sapiens (Human) 
2025-09-08 | PXD064939 | Pride
Autoimmunity Epithelial-mesenchymal transition (emt) Rho gtpase signaling Diora1 Mrck kinases Kinase inhibitory motif (kim) Cancer Cell motility Cytoskeleton Fam167a 
GenomicsAutoimmunity-associated DIORA1 binds the MRCK family of serine/threonine kinases and controls cell motility
Autoimmunity-associated DIORA1 binds the MRCK family of serine/threonine kinases and controls cell motility
PRJNA1274935 | ENA
UnknownAutoimmunity-associated DIORA1 binds the MRCK family of serine/threonine kinases and controls cell motility.
Not available
S-EPMC12519202 | biostudies-literature
TranscriptomicsAutoimmunity-associated DIORA1 binds the MRCK family of serine/threonine kinases and controls cell motility
Genetic association links DIORA1 to numerous autoimmune rheumatic diseases, including systemic lupus erythematosus, Sjögren's disease, rheumatoid arthritis, polymyositis and systemic sclerosis. However, its cellular function has remained unknown. Here, we identify the MRCK family of serine/threonine...
ORGANISM(S): Homo sapiens 
2025-09-08 | GSE299540 | GEO
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