Sort   by:  
 Page size 
TranscriptomicsJeB001: Elucidation of the distal convoluted tubule transcriptome identified new candidate players in magnesium balance
The distal convoluted tubule (DCT) plays a key role in the fine-tuning of renal Mg2+ reabsorption. In recent years, hereditary magnesium (Mg2+) transport disorders have helped to identify important players in DCT Mg2+ homeostasis. Here, we report the Mg2+-sensitive transcriptional expression of the ...
ORGANISM(S): Mus musculus 
2013-12-13 | E-GEOD-40208 | biostudies-arrayexpress
TranscriptomicsIdentification of renal distal convoluted tubules enriched genes
The renal distal convoluted tubule DCT is a short part of the distal nephron with specific functions transporting ions and thereby modifying Na, Ca, Mg, K balance A transcriptomic analysis of the DCT was performed to identify specific gene expression which would implicate those genes in specific DCT...
ORGANISM(S): Mus musculus 
2013-11-19 | E-GEOD-51935 | biostudies-arrayexpress
ProteomicsRapid Aldosterone Effects in Mouse Kidney Distal Convoluted Tubules Cells
Kidney distal convoluted tubules (DCT) are important for regulation of urinary salt excretion. Aldosterone is known to exert long-term effects in this segment, and regulate sodium reabsorption via increasing abundance of the Na+-Cl- cotransporter (NCC) and the epithelial Na channel ENaC. Whether acu...
ORGANISM(S): Mus musculus (Mouse) 
2019-06-24 | PXD010032 | Pride
Aldosterone Phosphoproteomics Quantification Distal convoluted tubules (dct) 
TranscriptomicsTranscription profiling of mouse nephron to assess circadian rhythms
Renal excretion of water and major electrolytes exhibits a significant circadian rhythm. This functional periodicity is believed to result, at least in part, from circadian changes in secretion/reabsorption capacities of the distal nephron and collecting ducts. Here, we studied the molecular mechani...
ORGANISM(S): Mus musculus 
2009-10-30 | E-GEOD-17739 | biostudies-arrayexpress
ProteomicsProteomic analysis of isolated mouse distal convoluted tubules following high potassium or low sodium diet
The “aldosterone paradox” is a poorly understood physiological mechanism in which increases in the hormone aldosterone either serve to stabilize blood pressure by increasing sodium-chloride (NaCl) reabsorption or to excrete potassium (K+). Under low NaCl intake, abundance and activity of the thiazid...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-30 | PXD014383 | Pride
Distal convoluted tubule Potassium Mouse Sodium Kidney Aldosterone 
GenomicsTime-resolved transcriptomic responses of kidney distal convoluted tubules induced by furosemide
Time-resolved transcriptomic responses of kidney distal convoluted tubules induced by furosemide
PRJNA1121400 | ENA
GenomicsHigh-resolution transcriptomic profiles of kidney distal convoluted tubules in male and female mice
High-resolution transcriptomic profiles of kidney distal convoluted tubules in male and female mice
PRJNA1121399 | ENA
TranscriptomicsIdentification of renal distal convoluted tubules enriched genes
The renal distal convoluted tubule DCT is a short part of the distal nephron with specific functions transporting ions and thereby modifying Na, Ca, Mg, K balance A transcriptomic analysis of the DCT was performed to identify specific gene expression which would implicate those genes in specific DCT...
ORGANISM(S): Mus musculus 
2013-11-19 | GSE51935 | GEO
ProteomicsAcute effects of Salbutamol in Mouse Kidney Distal Convoluted Tubules (mpkDCT) Cells
The sympathetic nervous system (SNS) plays a central role in blood pressure regulation. Recent studies have shown that cells of the distal convoluted tubule (DCT) can be stimulated directly via the beta-adrenergic receptor resulting in activation of the NaCl cotransporter NCC. Whether these effects ...
ORGANISM(S): Mus musculus (Mouse) 
2021-05-17 | PXD019051 | Pride
Beta2-adrenergic receptor Salbutamol Hypertention Dct 
TranscriptomicsHigh-resolution transcriptomic profiles of kidney distal convoluted tubules in male and female mice
Sexual dimorphic responses to physiological factors in the kidney have been emerging as important considerations for understanding kidney physiology and pathophysiology. Here, we report high-resolution transcriptome profiles of distal convoluted tubules isolated from the kidneys of male and female m...
ORGANISM(S): Mus musculus 
2026-06-30 | GSE269410 | GEO
Sort   by:  
 Page size