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Tabrizicola alba DMG-N-6 Genome sequencing and assembly
Generation of Syngeneic Orthotopic DMG Murine Models
We used MHC-I immunopeptidomics to study how MTX-241F, a selective EGFR/PI3K inhibitor, alters antigen presentation in diffuse midline glioma (H3K27M) and glioblastoma xenografts. MHC-I–bound peptides from vehicle- and drug-treated tumors were profiled by LC–MS/MS to identify tumor- and treatment-sp...
ORGANISM(S): Homo sapiens (Human) 
2026-02-10 | PXD070941 | Pride
Diffuse midline gliomas (DMG) are aggressive tumors with a poor prognosis. In this study, a technique called t-SNE analysis was used to cluster tumors based on their methylation profiles. DMG subtype with a co-occurrence of H3.3K27M and BRAF or FGFR1 mutations have been identified. This subtype has...
ORGANISM(S): Homo sapiens 
PRMT5 inhibition by LLY-283 in HSJD-DIPG-007 DMG cells
Diffuse Midline Glioma (DMG) syngeneic orthotopic murine mouse models were used as high fidelity model of human DMG tumors as they recapitulate the heterogeneity, cell states and OncoTarget/OncoTreat drug predictions of human DMG tumors.
ORGANISM(S): Mus musculus 
2025-12-22 | GSE262774 | GEO
Generation of Drug Perturbational Profiles in SF8628 and DIPG6 DMG Cell Lines
CRISPR/Cas9-mediated validation of candidate Master Regulators Proteins in DMG/GBM Cell Lines
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