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UnknownNanomechanical DNA origami pH sensors.
Not available
S-EPMC4239864 | biostudies-literature
ProteomicsProteomic Sensors for Quantitative, Multiplexed, and Spatial Monitoring of Kinase Signaling
Proteomic Kinase Activity Sensors (ProKAS) is a new technology developed to allow for quantitative and multiplexed analyses of kinase signaling in living cells with spatial resolution. Kinase sensors are expressed in cells as part of a ProKAS construct, which uses signal peptides to localize to spec...
ORGANISM(S): Homo sapiens (Human) 
2025-10-02 | PXD065795 | Pride
Proteomics atr atm chk1 dna damage genome maintenance signaling phosphoproteomics prm 
ProteomicsExpanding the biotechnological scope of metabolic sensors through computational-aided designs
Metabolic sensors are microbial strains modified such that biomass formation correlates with the availability of specific target metabolites. These sensors are essential for bioengineering (e.g. in growth-coupled selection of synthetic pathways), but their design is often time-consuming and low-thro...
ORGANISM(S): Escherichia coli 
2025-01-16 | PXD054993 | Pride
Shotgun proteomics Synthetic microbiology 
ProteomicsCyclophilin B function elucidated by electrochemical sensors
We have investigated the function of CypB through negative ionization high resolution LCMS and examined the purity of a CypB protein with intact mass analyzes on a Q Exactive mass spectrometer.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-05-19 | MSV000089498 | MassIVE
UnknownFluorescent DNA-based enzyme sensors.
Not available
S-EPMC5575859 | biostudies-literature
MetabolomicsGNPS - Ancestral allele of DNA polymerase gamma modifies antiviral tolerance
Mitochondria are arising as critical modulators of antiviral tolerance by releasing mtDNA/mtRNA fragments to cytoplasm upon infection, activating virus sensors and type-I interferon response. The relevance of these mechanisms for mitochondrial diseases remains understudied. Here, we investigated mit...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-12-11 | MSV000093634 | GNPS
GenomicsEstrogen-related receptors are targetable ROS sensors
Estrogen-related receptors are targetable ROS sensors
PRJNA603080 | ENA
UnknownMultiple cytosolic DNA sensors bind plasmid DNA after transfection.
Not available
S-EPMC6821305 | biostudies-literature
ProteomicsDisruption of mitochondrial dynamics triggers muscle inflammation through interorganellar contacts and mtDNA mislocation
Some forms of mitochondrial dysfunction induce sterile inflammation through mitochondrial DNA (mtDNA) recognition by intracellular DNA sensors. However, the involvement of mitochondrial dynamics mitigating such processes and their impact on muscle fitness remain unaddressed. Here we report that oppo...
ORGANISM(S): Homo sapiens (Human) 
2023-01-20 | PXD037935 | Pride
Mtdna Inflammation Dna sensors Endosomes Mitochondrial dynamics Muscle Atrophy 
UnknownMonitoring cooperative binding using electrochemical DNA-based sensors.
Not available
S-EPMC4303326 | biostudies-literature
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