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Drosophila heterochromatin protein 1- HP1 is believed to be involved in active transcription, transcriptional gene silencing, and the formation of heterochromatin2-7. However, little is known about the function of HP1 during development. Using a Gal4-induced RNA interference system, we show that con...
ORGANISM(S): Drosophila melanogaster 
30-day-old Cftr-/- homozygous for the S489X, B6.129P2-Cftr(tm1Unc), mutation or sibling wild-type control mice were treated with standard chow or 20 mg/kg/d rosiglitazone for 5 days. Colonic epithelial cells were extracted and mRNA isolated. Cftr-/- mice suffer from a severe intestinal phenotype inc...
ORGANISM(S): Mus musculus 
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