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UnknownHepatic DsbA-L protects mice from diet-induced hepatosteatosis and insulin resistance.
Not available
S-EPMC5434661 | biostudies-literature
UnknownApplication of a flipped classroom incorporating modified team-based learning in molecular biology laboratory teaching: a mixed methods study.
Not available
S-EPMC11653837 | biostudies-literature
UnknownGenome assembly of M. spongiola and comparative genomics of the genus Morchella provide initial insights into taxonomy and adaptive evolution.
Not available
S-EPMC11129363 | biostudies-literature
ProteomicsGlobal Phosphoproteomics Reveals Molecular Networks in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a systemic and heterogeneous autoimmune disease for which its treatment and phosphorylation-dependent regulatory mechanism remain elusive. Here, we aim to explore the molecular mechanism of phosphorylation regulation for SLE. We employed high-throughput Phosphop...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD025076 | Pride
Phosproteomics  sle remission stage  sle active stage  kinases  parallel reaction monitoring 
TranscriptomicsPathways leading to phosphorylation of p450c17 and to the post-translational regulation of androgen biosynthesis
Cytochrome P450c17 (P450c17) is the single enzyme that catalyzes steroid 17alpha-hydroxylase and 17,20 lyase activities and hence is the crucial decision-making step that determines the class of steroid made in a steroidogenic cell. Although both activities are catalyzed on a single active site, the...
ORGANISM(S): Homo sapiens 
2013-02-15 | E-GEOD-44311 | biostudies-arrayexpress
TranscriptomicsOrientation-Specific Joining of AID-initiated DNA Breaks Promotes Antibody Class Switching
During B cell development, RAG endonuclease cleaves immunoglobulin heavy chain (IgH) V, D, and J gene segments and orchestrates their fusion as deletional events that assemble a V(D)J exon in the same transcriptional orientation as adjacent Cμ constant region exons. In mice, six additional sets of c...
ORGANISM(S): Mus musculus 
2015-08-26 | E-GEOD-71005 | biostudies-arrayexpress
ProteomicsPodophyllum Hexandrum Royle MALDI-TOF-MS/MS
With the aim of reveal the mechanism of Podophyllum Hexandrum Royle adaption to high altitude, MALDI-TOF-MS/MS in combination with 2-DE was used to identify the differentially expressed proteins in leaves of Podophyllum Hexandrum Royle between low altitude (2200m) and high altitude (3100m), 65 diffe...
ORGANISM(S): Sinopodophyllum hexandrum 
2023-03-10 | PXD005640 | Pride
Podophyllum hexandrum royle Altitude Maldi-tof-ms/ms 
UnknownDNA methylation-based classification and identification of bladder cancer prognosis-associated subgroups.
Not available
S-EPMC7302382 | biostudies-literature
ProteomicsCharacterization of progressive denaturation and unfolding intermediates of proteins by fast cross-linking using di-ortho-phthalaldehyde
Chemical cross-linking of proteins coupled with mass spectrometry (CXMS) is widely used in protein structural analysis. In this study we develop a new class of non-hydrolyzable amine-selective di-ortho-phthalaldehyde (DOPA) cross-linkers, one of which is DOPA2. Cross-linking of proteins with DOPA2 i...
ORGANISM(S): Staphylococcus Aureus Bos Taurus 
2021-12-20 | PXD030552 |
UnknownVascular Protective Effects of Malus toringoides (Rehd.) Hughes Extracts and their Mechanism in Diabetic Rats and HUVECs.
Not available
S-EPMC9605824 | biostudies-literature
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