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TranscriptomicsDong M. oryzae MAPK pathway mutants
Gene expression profiling in MAPK-related mutants of Magnaporthe oryzae
ORGANISM(S): Magnaporthe oryzae 
2012-06-19 | E-MEXP-3658 | biostudies-arrayexpress
TranscriptomicsPathways leading to phosphorylation of p450c17 and to the post-translational regulation of androgen biosynthesis
Cytochrome P450c17 (P450c17) is the single enzyme that catalyzes steroid 17alpha-hydroxylase and 17,20 lyase activities and hence is the crucial decision-making step that determines the class of steroid made in a steroidogenic cell. Although both activities are catalyzed on a single active site, the...
ORGANISM(S): Homo sapiens 
2013-02-15 | E-GEOD-44311 | biostudies-arrayexpress
Unknown(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells.
Not available
S-EPMC4156762 | biostudies-literature
TranscriptomicsDiscovery of immediate YAP target genes with inducible form of YAP
Microarray analyses with cells/tissues overexpressing YAP have revealed many transcription targets of YAP (Dong et al, 2007; Zhao et al, 2008). However, as YAP induces transformation of non-cancerous cells, we thought many of known targets of YAP may be indirect consequence of transforming property ...
ORGANISM(S): Homo sapiens 
2015-11-23 | E-GEOD-60579 | biostudies-arrayexpress
UnknownImpact of ESR1 Gene Polymorphisms on Migraine Susceptibility: A Meta-Analysis.
Not available
S-EPMC4616512 | biostudies-literature
TranscriptomicsDisruption of transkingdom communication by antibiotics leads to immune and mitochondrial dysfunction in the gut (main)
We analyzed the effects of antibiotics using a popular model of gut microbiota depletion in mice by a cocktail of antibiotics. We combined intestinal transcriptome together with metagenomic analysis of the gut microbiota to develop a new bioinformatics approach that probes the links between microbia...
ORGANISM(S): Mus musculus 
2015-01-26 | E-GEOD-60566 | biostudies-arrayexpress
TranscriptomicsThe Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus
Pre-mRNA splicing is regulated by developmental and environmental cues, but little is known about how specific signals are transduced in mammalian cells to regulate this critical gene expression step. Here, we report massive reprogramming of alternative splicing in response to EGF signaling. By blo...
ORGANISM(S): Homo sapiens 
2012-08-17 | E-GEOD-37731 | biostudies-arrayexpress
UnknownEffects of low lead exposure on sperm quality and sperm DNA methylation in adult men.
Not available
S-EPMC8335892 | biostudies-literature
MetabolomicsEvidence of altered fatty acid metabolism in dogs with naturally occurring valvular heart disease and congestive heart failure

INTRODUCTION: Myxomatous mitral valve disease (MMVD) is the most common cardiac condition in adult dogs. The disease progresses over several years and affected dogs may develop congestive heart failure (HF). Research has shown that myocardial metabolism is altered in cardiac dise...

2022-03-31 | MTBLS716 | MetaboLights
TranscriptomicsDisruption of transkingdom communication by antibiotics leads to immune and mitochondrial dysfunction in the gut
We analyzed the effects of antibiotics using a popular model of gut microbiota depletion in mice by a cocktail of antibiotics. We combined intestinal transcriptome together with metagenomic analysis of the gut microbiota to develop a new bioinformatics approach that probes the links between microbia...
ORGANISM(S): Mus musculus 
2015-01-26 | E-GEOD-60568 | biostudies-arrayexpress
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