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ProteomicsDual-omics reveals the different roles of α1 and β-adrenergic receptors in acute sympathetic stress-induced cardiac inflammation
Sympathetic overactivation under strong acute stresses triggers acute cardiovascular events including myocardial infarction (MI), sudden cardiac death, and stress cardiomyopathy. α1-ARs and β-ARs, two dominant subtypes of adrenergic receptors in the heart, play a significant role in the physiologica...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-19 | PXD036011 | Pride
Adrenergic receptor Cardiac inflammation Acute sympathetic stress Dual-omics 
ProteomicsMulti-Omics of Spinal Ependymal Tumor
We conducted a multi-omics analysis of 25 patients, comprising 8 with ependymoma, 10 with myxopapillary ependymoma, and 7 with subependymoma, to identify both shared and distinct genomic, transcriptional, and proteomic features among these subtypes.
ORGANISM(S): Homo Sapiens 
2024-09-20 | PXD056112 |
ProteomicsPSAT1 impairs ferroptosis and reduces immunotherapy efficacy via GPX4 hydroxylation
MDA-MB-231 cells with expression of Flag-GPX4 were treated with IFNg. An immunoprecipitation assay was performed, and immunoprecipitates were subjected to masspec analysis.
ORGANISM(S): Homo Sapiens 
2025-03-01 | PXD061373 |
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