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MetabolomicsImpact of collection conditions on the metabolite content of human urine samples as analyzed by liquid chromatography coupled to mass spectrometry and nuclear magnetic resonance spectroscopy (LC-MS assay)
There is a lack of comprehensive studies documenting the impact of sample collection conditions on metabolic composition of human urine. To address this issue, two experiments were performed at a three-month interval, in which midstream urine samples from healthy individuals were collected, pooled, ...
2014-12-18 | MTBLS148 | MetaboLights
TranscriptomicsThe Extracellular RNA Quality Control (exRNAQC) study: RNA Exome sequencing of blood collection tube study (exRNAQC005)
To evaluate the impact of blood collection tubes on extracellular RNA (exRNA) sequencing, 10 different blood collection tubes were compared by applying RNA Exome sequencing (Illumina) to exRNA from human healthy donor plasma or serum. Three time spans between blood draw and downstream processing wer...
ORGANISM(S): Homo sapiens 
2021-06-10 | E-MTAB-10507 | biostudies-arrayexpress
TranscriptomicsThe Extracellular RNA Quality Control (exRNAQC) study: Small RNA sequencing of blood collection tube study (exRNAQC013)
To evaluate the impact of blood collection tubes on extracellular RNA (exRNA) sequencing, 10 different blood collection tubes were compared by applying Small RNA sequencing (Illumina) to exRNA from human healthy donor plasma or serum. Three time spans between blood draw and downstream processing wer...
ORGANISM(S): Homo sapiens 
2021-06-10 | E-MTAB-10506 | biostudies-arrayexpress
ProteomicsComparison of Transcript and Protein Abundance in Human Donor Retinas Support Extending Post-Mortem Interval from 12- to 18-hours to Expand the Donor Pool for Biomedical Research
Extending the post-mortem interval (PMI) from 12- to 18-hours was done to see if transcript and protein abundance in the human retina changed. Donor eyes were recovered from post-mortem donors (n=7 pairs) and stored at 2–8°C. Only donor eyes with ocular cooling within 8 hours of death were examined....
ORGANISM(S): Homo sapiens (Human) 
2026-04-07 | PXD068030 | Pride
Tmtpro Mass spectrometry Retina Orbitrap tribrid sps-ms3 acquisition Donor collection time Isobaric labeling quantitative proteomics 
TranscriptomicsThe Extracellular RNA Quality Control (exRNAQC) study: Small RNA sequencing of interaction study (exRNAQC017)
Study to detect possible interactions between blood collection tubes and RNA purification methods on extracellular RNA (exRNA) sequencing. Different combinations of blood collection tubes (3 in total), time intervals between blood draw and downstream processing (immediate (T0), after 4 hours (T4), a...
ORGANISM(S): Homo sapiens 
2022-12-25 | E-MTAB-12542 | biostudies-arrayexpress
TranscriptomicsLocal regulation and clinical impact of complement gene expression in deceased and living donor kidney allografts
The biopsy samples obtained at implantation segregated in 2 distinct groups according to donor origin, with a cluster of 319 unique identified genes higher expressed in DD compared to LD kidneys, and 329 genes lower expressed (false discovery rate <5%). Using pathway analysis software a significant ...
ORGANISM(S): Homo sapiens 
2008-04-16 | E-GEOD-11166 | biostudies-arrayexpress
TranscriptomicsThe Extracellular RNA Quality Control (exRNAQC) study: RNA Exome sequencing of interaction study (exRNAQC017)
Study to detect possible interactions between blood collection tubes and RNA purification methods on extracellular RNA (exRNA) sequencing. Different combinations of blood collection tubes (3 in total), time intervals between blood draw and downstream processing (immediate (T0), after 4 hours (T4), a...
ORGANISM(S): Homo sapiens 
2022-12-25 | E-MTAB-12541 | biostudies-arrayexpress
TranscriptomicsGlobal Gene Expression in Deceased Donor Liver Transplantation with Ischemic Preconditioning
The clear benefits of ischemic preconditioning (IPC) in reducing ischemia reperfusion injury (IRI) remain indistinct in human liver transplantation. To further understand the mechanistic aspects of IPC in human deceased donor liver transplantation (DDLT), we performed microarray analyses to determin...
ORGANISM(S): Homo sapiens 
2010-05-20 | E-GEOD-15480 | biostudies-arrayexpress
TranscriptomicsComprehensive gene expression profile of human livers from patients with biliary atresia at the time of diagnosis and the corresponding disease and normal controls
Liver biopsy samples were obtained from 64 infants with biliary atresia at the time of intraoperative cholangiogram. Liver biopsy samples were obtained from 14 age-matched infants with other causes of intrahepatic cholestasis, and from 7 deceased-donor children. GeneChip® Human Gene 1.0 ST Array (Af...
ORGANISM(S): Homo sapiens 
2013-06-01 | E-GEOD-46960 | biostudies-arrayexpress
TranscriptomicsSteroid Pretreatment of Organ Donors to Prevent Postischemic Renal Allograft Failure: A Randomized, Controlled Trial
Comparison between pretreated donor grafts corticosteroid vs. placebo Prospective, randomised, double-blind, placebo-control trial, xls files contain normalized data (Default Total Intensity Normalization, see Stanford Microarray Database website), gpr files the raw data
ORGANISM(S): Homo sapiens 
2010-08-17 | E-GEOD-14700 | biostudies-arrayexpress
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