Downes D D - OmicsDI

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Unknown (253)
Genomics (57)
Transcriptomics (15)
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Homo sapiens (61)
Mus musculus (13)
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EGA (53)
biostudies-arrayexpress (19)
pride (4)
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ILLUMINA, Illumina HiSeq 2000 (1)
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Instrument Platform

Gas Chromatography MS - positive (1)
Liquid Chromatography MS - negative - reverse phase (1)
Liquid Chromatography MS - positive - reverse phase (1)

Publication Date

2013 (5)
2015 (4)
2012 (4)
2014 (3)
2009 (2)
2025 (2)
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2011 (1)
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CHEBI ID

CHEBI:10043 (1)
CHEBI:10072 (1)
CHEBI:102485 (1)
CHEBI:104011 (1)
CHEBI:110187 (1)
CHEBI:1142 (1)
CHEBI:116314 (1)
CHEBI:131145 (1)
CHEBI:131659 (1)
CHEBI:131691 (1)
CHEBI:131738 (1)
CHEBI:131743 (1)
CHEBI:131887 (1)
CHEBI:131924 (1)
CHEBI:131989 (1)
CHEBI:132853 (1)
CHEBI:132958 (1)
CHEBI:132968 (1)
CHEBI:133028 (1)
CHEBI:133057 (1)
CHEBI:133077 (1)
CHEBI:133144 (1)
CHEBI:133148 (1)
CHEBI:133456 (1)
CHEBI:133512 (1)
CHEBI:133599 (1)
CHEBI:133617 (1)
CHEBI:133623 (1)
CHEBI:133657 (1)
CHEBI:133731 (1)

Metabolite Name

(+)-2-Sterpurene-6,12,15-triol (1)
(+)-8-hydroxycalamenene (1)
(+)-Norushinsunine N-oxide (1)
(-)-Neolinderatin (1)
(-)-Stercobilin (1)
(10betaH,11xi)-11-Hydroxy-13-nor-6-eremophilen-8-one (1)
(1R,16Z,24E,26E,28Z)-1,18-dihydroxy-12-[1-(4-hydroxy-3-methoxycyclohexyl)propan-2-yl]-19,30-dimethoxy-15,17,21,23,29-pentamethyl-35-methylidene-11,36-dioxa-4-azatricyclo[30.3.1.0?,?]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (1)
(1R,2R)-3-oxo-2-pentyl-cyclopentanehexanoic acid (1)
(1S,2S)-3-oxo-2-pentyl-cyclopentanebutanoic acid (1)
(22E)-3alpha,6beta,7beta-Trihydroxy-5beta-chol-22-en-24-oic Acid (1)
(25S)-5alpha-cholestan-3beta,4beta,6alpha,8beta,15alpha,16beta,26-heptol (1)
(2E,4E)-2,4-Octadien-1-ol (1)
(2R,2'S)-Isobuteine (1)
(2R,3R,4R)-2-Amino-4-hydroxy-3-methylpentanoic acid (1)
(2S,4S)-Pinnatanine (1)
(3E,5Z)-3,5-Octadien-1-ol (1)
(3S,5R,6R,7E)-3,5,6-Trihydroxy-7-megastigmen-9-one (1)
(4E,6E,d14:2) sphingosine (1)
(4E,8E,10E-d18:3)sphingosine (1)
(4E,8E,9Me-d19:2)sphingosine (1)
(4E,8E,d18:2) sphingosine (1)
(4S,8R)-8,9-Dihydroxy-p-menth-1(6)-en-2-one (1)
(5alpha,6beta,14alpha,20R,22R)-5,6,14,20,27-Pentahydroxy-1-oxowith-24-enolide (1)
(6E,8E,10R,12Z)-10-Hydroxy-3-oxooctadecatrienoic acid (1)
(6S)-dehydrovomifoliol (1)
(9R,13R)-1a,1b-dihomo-jasmonic acid (1)
(9S,13S)-1a,1b-dihomo-jasmonic acid (1)
(E)-10-Oxo-8-decenoic acid (1)
(E)-2-Butenyl-4-methyl-threonine (1)
(E)-2-O-Cinnamoyl-beta-D-glucopyranose (1)

Study type

Transcription profiling by array (8)
RNA-seq of coding RNA (7)
ChIP-seq (4)

Release Date

2022 (33)
2025 (31)
2020 (30)
2017 (22)
2024 (19)
2021 (17)
2019 (17)
2023 (16)
2015 (12)
2013 (11)
2018 (10)
2016 (10)
2012 (9)
2014 (8)
2009 (8)
2008 (7)
2011 (6)
2007 (2)
2026 (1)
2010 (1)
2006 (1)
2004 (1)

Lab affiliation

Bristol Myers Squibb (1)
Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA (1)
Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. Otto-Hahn-Straße 6b 44227 Dortmund, Germany P: +49 (0)2 31.13 92-100 F: +49 (0)2 31.13 92-200 www.isas.de (1)
Stoller Biomarker Discovery Centre, University of Manchester, United kingdom (1)

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Vitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy

The poor clinical outcome in pancreatic ductal adenocarcinoma (PDA) has been attributed to intrinsic resistance to chemotherapy and a growth-permissive tumor microenvironment. Quiescent pancreatic stellate cells (PSCs) are neuroendocrine, nestin-positive, lipid-accumulating cells whose homologues i...

ORGANISM(S): Mus musculus

2014-10-03 | E-GEOD-43770 | biostudies-arrayexpress

A master cistromic circuit governing hepatic fibrogenesis [ChIP-seq]

Liver fibrosis is a reversible wound-healing response to liver injury and hepatic stellate cells (HSCs) are central cellular players that mediate hepatic fibrogenesis. However, the molecular mechanisms that govern this process remain unclear. Here, we reveal a novel cistromic circuit in HSCs compris...

ORGANISM(S): Homo sapiens

2013-04-29 | E-GEOD-38103 | biostudies-arrayexpress

Design, modular synthesis and screening of 58 shape-diverse 3-D fragments.

Not available

S-EPMC12486152 | biostudies-literature

A master cistromic circuit governing hepatic fibrogenesis [expression array]

Liver fibrosis is a reversible wound-healing response to liver injury and hepatic stellate cells (HSCs) are central cellular players that mediate hepatic fibrogenesis. However, the molecular mechanisms that govern this process remain unclear. Expression profiling was used to explore the potential im...

ORGANISM(S): Rattus norvegicus

2013-04-29 | E-GEOD-41579 | biostudies-arrayexpress

Vitamin D Switches BAF Complexes to Protect β Cells.

Not available

S-EPMC5987229 | biostudies-literature

Systematic improvement of isobutanol production from D-xylose in engineered Saccharomyces cerevisiae.

Not available

S-EPMC6787123 | biostudies-literature

Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.

Not available

S-EPMC4177038 | biostudies-literature

Cistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-dependent autoimmune diseases.