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TranscriptomicsWild-Type Nras Lacks Tumor Suppressor Activity and Nras Oncogene Dosage Strongly Modulates Hematopoietic Transformation
Contemporary treatment of pediatric acute myeloid leukemia (AML) requires the assignment of patients to specific risk groups. To explore whether expression profiling of leukemic blasts could accurately distinguish between the known risk groups of AML, we analyzed 130 pediatric and 20 adult AML diagn...
ORGANISM(S): Homo sapiens 
2013-07-02 | E-GEOD-43176 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for pediatric acute myeloid leukemia (AML) samples at diagnosis: Xba SNP array
Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML. This study characterizes the CNA and LOH in a representative cross-section through subtypes of pediatric AML. Affymetrix SNP arrays were performed according to ...
ORGANISM(S): Homo sapiens 
2010-01-03 | E-GEOD-15732 | biostudies-arrayexpress
TranscriptomicsAffymetrix U133A array data for 111 pediatric acute myeloid leukemia (AML) samples at diagnosis
Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML This study characterizes CNA and LOH, gene expression and gene sequence mutations in a representative cross-section through subtypes of pediatric AML. Keywords...
ORGANISM(S): Homo sapiens 
2010-01-03 | E-GEOD-14471 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for pediatric acute myeloid leukemia (AML) samples at diagnosis: Nsp SNP Array
Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML. This study characterizes the CNA and LOH in a representative cross-section through subtypes of pediatric AML. Affymetrix SNP arrays were performed according to ...
ORGANISM(S): Homo sapiens 
2010-04-13 | E-GEOD-15730 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for pediatric acute myeloid leukemia (AML) samples at diagnosis: Sty2 SNP array
Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML. This study characterizes the CNA and LOH in a representative cross-section through subtypes of pediatric AML. Affymetrix SNP arrays were performed according to ...
ORGANISM(S): Homo sapiens 
2010-01-03 | E-GEOD-15731 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for pediatric acute myeloid leukemia (AML) samples at diagnosis: Hind SNP array
Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML. This study characterizes the CNA and LOH in a representative cross-section through subtypes of pediatric AML. Affymetrix SNP arrays were performed according to ...
ORGANISM(S): Homo sapiens 
2010-01-03 | E-GEOD-15714 | biostudies-arrayexpress
TranscriptomicsFunctional Evidence Implicating Chromosome 7q22 Haploinsufficiency in Myelodysplastic Syndrome Pathogenesis
Purpose: 5A3+/del mice, which have a heterozygous germ line deletion of a 2-Mb interval of chromosome band 5A3 syntenic to a commonly deleted segment of human 7q22, exhibit hematopoietic stem cell (HSC) abnormalities that may contribute to myelodysplastic syndrome (MDS) pathogenesis. These defects a...
ORGANISM(S): Mus musculus 
2015-09-09 | E-GEOD-72811 | biostudies-arrayexpress
UnknownComparative analysis of different approaches to measure treatment response in acute myeloid leukemia.
Not available
S-EPMC3462046 | biostudies-literature
UnknownChildhood Acute Lymphoblastic Leukemia: Progress Through Collaboration.
Not available
S-EPMC4567699 | biostudies-literature
UnknownWhat Constitutes High-Quality Paediatric Palliative Care? A Qualitative Exploration of the Perspectives of Children, Young People, and Parents.
Not available
S-EPMC12408654 | biostudies-literature
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