An iTRAQ-based proteomics analysis was performed on BMDM to screen out the potential downstream target molecules of YKL-40 in regulating macrophage apoptosis.
To further investigate the mechanism how the decline in Notch signaling induces premature senescence in endothelial cells, we performed microarray analysis and identified Id1 nd DUSP1 as the downstream molecules of Notch pathway. In quantitative PCR and western blot analyses, the expression level of...
Identification of downstream molecules associated with TLR4-dependent inflammatory response in primary bone marrow-derived macrophages (BMDMs) by PolyA-RNA sequencing.
To further investigate the mechanism how the decline in Notch signaling induces premature senescence in endothelial cells, we performed microarray analysis and identified Id1 nd DUSP1 as the downstream molecules of Notch pathway. In quantitative PCR and western blot analyses, the expression level of...
This model is from the article:
Temporal Coding of Insulin Action through Multiplexing of the AKT Pathway.
Kubota H, Noguchi R, Toyoshima Y, Ozaki Y, Uda S, Watanabe K, Ogawa W, Kuroda S. Mol Cell.
2012 Jun 29;46(6):820-32. 22633957
, ...
NGF dependent Akt pathway model
made by Kazuhiro A. Fujita.
This is the NGF
dependent Akt pathway model described in:
Decoupling of receptor and downstream signals in the Akt pathway by its low-pass ...
Akt pathway model with EGFR inhibitor
made by Kazuhiro A. Fujita.
This is the Akt pathway model with an EGFR inhibitor described in:
Decoupling of receptor and downstream signals in the Akt pathway by ...
EGF dependent Akt pathway model
made by Kazuhiro A. Fujita.
This is the EGF dependent Akt pathway model described in:
Decoupling of receptor and downstream signals in the Akt pathway by its low-pass filter characte...
The human nm23-H1 was discovered as a tumor metastasis suppressor based on its reduced expression in melanoma cell lines with low versus high metastatic potential. It encodes for one of two subunits of the nucleoside-diphosphate kinase. Besides its role in the maintenance of the cells NTP pool, nm23...
