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ProteomicsDownstream Molecules of YKL-40 in Regulating Apoptosis in BMDM
An iTRAQ-based proteomics analysis was performed on BMDM to screen out the potential downstream target molecules of YKL-40 in regulating macrophage apoptosis.
ORGANISM(S): Mus musculus (Mouse) 
2022-02-15 | PXD028305 | Pride
Ykl-40 Bmdm Apoptosis Downstream molecules 
GenomicsEffect of YKL-40 on melanoma proliferation in a mouse model.
Effect of YKL-40 on melanoma proliferation in a mouse model.
PRJNA899722 | ENA
TranscriptomicsYKL-40 alleviates the TNF-α-Induced chondrocyte injury in osteoarthritis in vitro
Background: Osteoarthritis (OA) is a degenerative joint disease with high global prevalence, and YKL-40 is an important factor related to the pathological process of OA. Increased levels of YKL-40 exert a protective influence against TNF-α-induced apoptosis in chondrocytes, thereby enhancing chondro...
ORGANISM(S): Oryctolagus cuniculus 
2026-07-01 | GSE328136 | GEO
TranscriptomicsEffect of YKL-40 on melanoma proliferation in a mouse model.
To investigate the effect of YKL-40 on melanoma proliferation in C57BL/6J mice, we established a B16F10 cell line overexpressing YKL-40. Then we used the cells for subcutaneous injection into mice, thereby establishing a tumor model. Finally, we performed gene expression profiling using data obtaine...
ORGANISM(S): Mus musculus 
2024-09-10 | GSE217590 | GEO
GenomicsThe different role of YKL-40 in glioblastoma is a function of MGMT promoter methylation status
The different role of YKL-40 in glioblastoma is a function of MGMT promoter methylation status
PRJNA644111 | ENA
UnknownSystemic Immune Modulation in Gliomas: Prognostic Value of Plasma IL-6, YKL-40, and Genetic Variation in YKL-40.
Not available
S-EPMC7180208 | biostudies-literature
UnknownElevated YKL-40 and low sAPPβ:YKL-40 ratio in antemortem cerebrospinal fluid of patients with pathologically confirmed FTLD.
Not available
S-EPMC6351153 | biostudies-literature
UnknownYKL-40, a secreted glycoprotein, promotes tumor angiogenesis.
Not available
S-EPMC2795793 | biostudies-literature
TranscriptomicsThe different role of YKL-40 in glioblastoma is a function of MGMT promoter methylation status
To explore what could distinguish the difference in the function of YKL-40 in GSCs, we performed RNA-Seq to identify the molecular subclasses of each GSC
ORGANISM(S): Homo sapiens 
2023-07-01 | GSE153794 | GEO
UnknownRelB/p50 complexes regulate cytokine-induced YKL-40 expression.
Not available
S-EPMC4355396 | biostudies-literature
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