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GenomicsAnalysis of differential miRNA expression in mineralising DPCs treated with pharmacological epigenetic inhibitors.
Analysis of differential miRNA expression in mineralising DPCs treated with pharmacological epigenetic inhibitors.
PRJNA953388 | ENA
GenomicsAnalysis of differential miRNA expression in mineralising DPCs treated with pharmacological epigenetic inhibitors.
To establish a miRNA expression profile for DPCs undergoing epigenetically-mediated mineralisation, rodent DPCs were induced to mineralise and treated with a HDAC inhibitor, SAHA, and a DNMT inhibitor, 5-AZA-CdR. RNA was then isolated from DPCs at day 4 of culture and subjected to RNA sequencing. Su...
ORGANISM(S): Rattus norvegicus 
2023-07-31 | GSE229197 | GEO
TranscriptomicsHypoxia-enhanced Derivation of iPSCs from Human Dental Pulp Cells
Hypoxia enhances the reprogramming efficiency of human dermal fibroblasts to become induced pluripotent stem cells (iPSCs). Because we showed previously that the hypoxia facilitates the isolation and maintenance of human dental pulp cells (DPCs), we examined here whether it promotes the reprogrammin...
ORGANISM(S): Homo sapiens 
2013-09-03 | E-GEOD-45872 | biostudies-arrayexpress
Genomics
RNA-sequencing of mice primary DPCs and novel three-dimensional DPCs (tdDPCs)
PRJNA923809 | ENA
UnknownCDC42-mediated Wnt signaling facilitates odontogenic differentiation of DPCs during tooth root elongation.
Not available
S-EPMC10510226 | biostudies-literature
Genomics
RNA-seq of three-dimensional DPCs or PBS treated Huvecs
PRJNA890242 | ENA
ProteomicsDNA-protein crosslinkings (DPCs) in S. cerevisiae for methanol utilization
Formaldehyde-induced DNA-protein crosslinkings (DPCs) and large repeated DNA fragments suggest strategies for methanol detoxification and phenotype enhancement
ORGANISM(S): Saccharomyces Cerevisiae 
PXD064225 |
ProteomicsFlap endonuclease 1 repairs DNA-protein crosslinks via ADP-ribosylation
The protein composition of DNA-protein crosslinks (DPCs) induced by formaldehyde treatment of human cell lines was analyzed by mass spectrometry.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-06-14 | MSV000095039 | MassIVE
ProteomicsMetalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Removal
Cytotoxicity of DNA-protein crosslinks (DPCs) is ascribed largely to their ability to block the progression of DNA replication fork. DPCs are frequently occurring in cells, either as a consequence of metabolism or exogenous agents. The mechanism of DPCs removal is not completely understood. Here, we...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080743 | MassIVE
ProteomicsHuman dermal papilla cell culture medium iTRAQ
Alopecia is an exceedingly prevalent problem and lacks effective therapy. Recently, research has focused on early-passage dermal papilla cells (DPCs), which have hair inducing activity both in vivo and in vitro. Our previous study indicated that factors secreted from early-passage DPCs contribute to...
ORGANISM(S): Homo sapiens (Human) 
2018-10-26 | PXD004201 | Pride
Human Dermal papilla cell Itraq 
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