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MicroRNAs (miRNAs) are essential regulators involved in multiple biological processes. To achieve their gene repression function, they are loaded in miRNA-specific Argonautes to form the miRNA-induced silencing complex (miRISC). Mammals and C. elegans possess more than one paralog of miRNA-specific ...
ORGANISM(S): Caenorhabditis elegans 
2025-03-06 | PXD055867 | Pride
Transcriptional profiling of 3 dpf and 5 dpf WT zebrafish intestinal epithelial cells
Dipeptidyl peptidase DPF-3 is a gatekeeper of microRNA Argonaute compensation in animals
This microarray was performed in attempt to find (novel) related genes in the msp/ron signaling pathway during embryonic development Embryos from mutant versus wild type crosses were raised in standard E3 medium at 28 degrees Celcius. At 3 dpf and 6 dpf total RNA from (n=30) msp mutant versus wild t...
ORGANISM(S): Danio rerio 
The zebrafish is a powerful model for the study of hematopoietic stem and progenitor cells (HSPC). We have developed a novel HSPC-specific transgenic line (Runx1+23:GFP). We have used this line in time-lapse live imaging studies to track the migration of HSPC during development. We have also perform...
ORGANISM(S): Danio rerio 
For this experiment, we analyzed gene expression changes and intron splicing events in the WT zebrafish intestine at two developmental stages (3 dpf and 5 dpf). To perform this analysis, we collected > 125 M paired end reads from total RNA isolated from purified cldn15la+ intestinal epithelial cells...
ORGANISM(S): Danio rerio 
2026-08-02 | GSE341768 | GEO
RNA-seq of microglia from 3-dpf siblings, mafba and mafbb single mutant and DMut zebrafish
MicroRNAs (miRNAs) are essential regulators involved in multiple biological processes. To achieve their gene repression function, they are loaded in miRNA-specific Argonautes to form the miRNA-induced silencing complex (miRISC). Mammalians and C. elegans intriguingly possess more than one paralog of...
ORGANISM(S): Caenorhabditis elegans 
2025-03-06 | GSE276186 | GEO
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