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Laboratory of Molecular Neuro-Oncology, Department of Neurology, Clinical Neuroscience Center, University Hospital and University of Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland Department of Neurosurgery, Cantonal Hospital St.Gallen, Rorschacher Strasse 95, 9007 St.Gallen, Switzerland (1)
Ludwig Institute for Cancer Research Lausanne Centre de recherche Agora Rue du Bugnon 25A CH-1011 Lausanne (1)
Nutritional Sciences, Division of Agriculture, Life and Veterinary Sciences, University of Arizona, Tucson, Arizona 85721, USA (1)
Sanquin Research, Amsterdam, NL (1)
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Machine learning reveals limited contribution of trans-only encoded variants to the HLA-DQ immunopeptidome

HLA-DQ molecules can be formed as both cis and trans variants. So far, the progress for predicting HLA-DQ antigen presentation has been limited. In addition, the contribution of trans-only variants in shaping the HLA-DQ immunopeptidome remains largely unresolved. Here, we address these issues by int...

ORGANISM(S): Homo sapiens (Human)

2023-05-10 | PXD040860 | Pride