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ProteomicsiTRAQ LLC-PK1 CnI - Sum of peak intensities outperforms peak area integration in iTRAQ protein expression measurement by LC-MS/MS using a TripleTOF 5600+ platform
In the field of quantitative proteomics, the Isobaric Tags for Relative & Absolute Quanti-tation (iTRAQ) technology has demonstrated efficacy for proteome monitoring despite its lack of a consensus for data handling. In this study, after peptide and protein identification, we com-pared the widesprea...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2019-08-19 | PXD007891 | Pride
Llc pk-1 Itraq Calcineurin inhibitors 
TranscriptomicsTime-course gene expression profiles of gefitinib-sensitive or -resistant lung adenocarcinoma cells stimulated with EGF, in the presence or absence of gefitinib, EGF receptor tyrosine kinase-specific inhibitor
Gefitinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), induces substantial clinical responses for non-small cell lung cancer (NSCLC) cells harboring EGFR activating mutations, but most of them invariably develop resistance. By generating a gefitinib resistance (PC9GR)...
ORGANISM(S): Homo sapiens 
2014-01-01 | E-GEOD-34228 | biostudies-arrayexpress
TranscriptomicsMicroarray analyses of rachis tissue extracted from control and BS affected grape clusters
Transcriptional expression in the rachis of pre-sympotmatic (T1) and symptomatic (T2) berry shrivel (BS) clusters in comparison to control samples. Samples were collected from a vineyard in Mailberg, Lower Austria, in 2011 from cultivar Blauer Zweigelt (Vitis vinifera) grafted on Kober 5BB. The obje...
ORGANISM(S): Vitis vinifera 
2022-09-01 | E-MTAB-12113 | biostudies-arrayexpress
UnknownGenome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication.
Not available
S-EPMC3494089 | biostudies-literature
TranscriptomicsBrain transcriptome variation among behaviorally distinct strains of zebrafish (Danio rerio)
Domesticated animal populations often show profound reductions in predator avoidance and fear-related behavior compared to wild populations. These reductions are remarkably consistent and have been observed in a diverse array of taxa including fish, birds, and mammals. Experiments conducted in com...
ORGANISM(S): Danio rerio 
2012-06-14 | E-GEOD-38729 | biostudies-arrayexpress
TranscriptomicsCharacterization of cyclobutane pyrimidine dimer-dependent modulation of gene expression in human keratinocytes following UVB exposure
To address CPD-dependent UVB activities, a model system was established in which transfection of keratinocytes with pseudouridine-modified mRNA (M-NM-(-mRNA) encoding CPD-photolyase resulted in 90% reduction of CPDs within 6 and 24 hours after UVB exposure. Microarray analysis of this model system d...
ORGANISM(S): Homo sapiens 
2015-01-16 | E-GEOD-65034 | biostudies-arrayexpress
UnknownRucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial.
Not available
S-EPMC5901715 | biostudies-literature
UnknownEpidemiological Changes and Improvement in Outcomes of Infective Endocarditis in Europe in the Twenty-First Century: An International Collaboration on Endocarditis (ICE) Prospective Cohort Study (2000-2012).
Not available
S-EPMC10147876 | biostudies-literature
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