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Genotypic differences greatly influence susceptibility and resistance to disease. Understanding genotype-phenotype relationships requires that phenotypes be viewed as manifestations of network properties, rather than simply as the result of individual genomic variations. Genome sequencing efforts ha...
ORGANISM(S): Homo sapiens 
Atherosclerosis is the main underlying cause of cardiovascular diseases (CVDs). Its prevention is based on the detection and treatment of traditional cardiovascular risk factors1 but often fails to identify individuals at risk for early vascular disease2. Recent research has suggested new players in...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-15 | PXD063955 | Pride
Breast cancer is a genetically and phenotypically complex disease. To understand the role of microRNAs in this molecular complexity, we performed miRNA expression analysis in a cohort of molecularly well-characterized human breast cancer (BC) cell lines to discover miRNAs associated with the most co...
ORGANISM(S): Homo sapiens 
Uveal melanoma (UM) is a rare form of melanoma with a genetics and immunology that is different from skin melanoma. Previous studies have identified genetic driver events of early stage disease when the tumor is confined to the eye. In this study, we have characterized genomic events in UM metastase...
ORGANISM(S): Homo sapiens (Human) 
2020-03-18 | PXD017743 | Pride
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