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ProteomicsCrosstalk between Drp1 phosphorylations during mitochondrial remodelling and their impact on metabolic adaptation - Parallel reaction monitoring (PRM) mass spectrometry-based proteomic data
Mitochondria constantly undergo fusion and fission events, referred as mitochondrial dynamics, which determine intracellular mitochondrial architecture and bioenergetics. Cultured cell studies demonstrate that mitochondrial dynamics are acutely regulated by phosphorylation of the mitochondrial fissi...
ORGANISM(S): Mus musculus (Mouse) 
2021-08-26 | PXD027108 | Pride
Prm Mouse Drp1 Phosphorylation 
ProteomicsIdentification of phosphorylation sites on purified recombinant protein Dynamin-like protein 1
Drp1 is a GTPase involves in mitochondrial division. The phosphorylation of Drp1 is reported to influence Drp1 activity. Two well known Drp1 phosphorylation sites have been identified. In here, we in vitro phosphorylate S579 site by ERK2 kinase on WT-Drp1 or S600D-Drp1 mutant and try to identify the...
ORGANISM(S): Homo sapiens (Human) 
2024-06-16 | PXD046824 | Pride
Drp1-s600 Mitochondria Drp1-s579 Phosphorylation 
UnknownEffects of phosphorylation on Drp1 activation by its receptors, actin, and cardiolipin.
Not available
S-EPMC10881151 | biostudies-literature
UnknownEffects of phosphorylation on Drp1 activation by its receptors, actin, and cardiolipin.
Not available
S-EPMC10462108 | biostudies-literature
UnknownCrosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation.
Not available
S-EPMC8411118 | biostudies-literature
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