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MetabolomicsRepurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides are the gold standard for insect control, they neg...
2021-10-06 | MTBLS2166 | MetaboLights
TranscriptomicsDissecting the Mycobacterium bovis BCG response to macrophage infection to identify targets for anti-tuberculosis drug and vaccine discovery
New strategies are required to reduce the worldwide burden of tuberculosis. Intracellular survival and replication of Mycobacterium tuberculosis after macrophage phagocytosis is a fundamental step in the complex host-pathogen interactions that lead to granuloma formation and disease. Greater underst...
ORGANISM(S): Mycobacterium tuberculosis variant bovis BCG str. Pasteur 1173P2 
2022-01-14 | E-MTAB-11107 | biostudies-arrayexpress
GenomicsRational identification of novel drug targets and vaccine candidates against the cattle tick, Rhipicephalus microplus
Rational identification of novel drug targets and vaccine candidates against the cattle tick, Rhipicephalus microplus
PRJNA915116 | ENA
GenomicsDissecting the Mycobacterium bovis BCG response to macrophage infection to identify targets for anti-tuberculosis drug and vaccine discovery
Dissecting the Mycobacterium bovis BCG response to macrophage infection to identify targets for anti-tuberculosis drug and vaccine discovery
PRJEB48468 | ENA
GenomicsMolecular epidemiology of Plasmodium falciparum drug resistance and vaccine targets in high-transmission settings in Africa
Genomic surveillance of Plasmodium falciparum drug resistance and Vaccine target markers
PRJEB96043 | ENA
GenomicsMolecular epidemiology of Plasmodium falciparum drug resistance and vaccine targets in high-transmission settings in Africa
Genomic surveillance of Plasmodium falciparum drug resistance and Vaccine target markers
PRJEB91231 | ENA
ProteomicsA SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Purposing
An outbreak of the novel coronavirus SARS-CoV-2, the causative agent of COVID-19 respiratory disease, has infected over 170,000 people since the end of 2019, killed over 7,400, and caused worldwide social and economic disruption. SARS-CoV-2 infection has a mortality rate of 3.4% among confirmed case...
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 (ncbitaxon:2697049) Homo Sapiens (ncbitaxon:9606) 
2020-03-24 | MSV000085144 | MassIVE
TranscriptomicsRational identification of novel drug targets and vaccine candidates against the cattle tick, Rhipicephalus microplus
Control of complex parasites via vaccination remains challenging, with the current combination of vaccines and small drugs remaining the choice of control strategy. The development of new vaccines against complex endo- and ectoparasites remains challenging and more studies are providing evidence tha...
ORGANISM(S): Rhipicephalus microplus 
2023-10-23 | GSE221646 | GEO
UnknownIdentification of vaccine and drug targets in Shigella dysenteriae sd197 using reverse vaccinology approach.
Not available
S-EPMC8742002 | biostudies-literature
UnknownMulti-epitope chimeric vaccine designing and novel drug targets prioritization against multi-drug resistant Staphylococcus pseudintermedius.
Not available
S-EPMC9386485 | biostudies-literature
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