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TranscriptomicsGene expression profiling of Human Umbilical Vein Endothelial Cells (HUVEC) after treatment with Erg or control antisense (GeneBloc)
The endothelial transcription factor Erg (Ets Related Gene) plays an important role in homeostasis and angiogenesis by regulating many endothelial functions including survival and junction stability. Here we show that Erg regulates endothelial cell migration. Transcriptome profiling of Erg-deficient...
ORGANISM(S): Homo sapiens 
2012-02-27 | E-GEOD-32984 | biostudies-arrayexpress
GenomicsUnbiased Capture Hi-C reveals the potential targets of breast cancer susceptibility loci
Genome-wide association studies have identified over 70 common variants that are associated with breast cancer risk. Most of these variants map to non-protein-coding regions; several map to gene deserts, regions of several hundred kb lacking protein-coding genes. We hypothesized that gene deserts ha...
ORGANISM(S): Homo sapiens 
2014-08-04 | E-GEOD-55634 | biostudies-arrayexpress
Genomicsena-DATASET-ICR-PTGT-05-02-2015-11:21:41:591-6 - samples
Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci.
EGAD00001001243 | EGA
GenomicsCapture Hi-C identifies the chromatin interactome of colorectal cancer risk loci
Multiple regulatory elements distant to their targets on the linear genome can influence the expression of a single gene through chromatin looping. Chromosome conformation capture implemented in Hi-C allows for genome-wide agnostic characterization of chromatin contacts. However, detection of functi...
EGAS00001001085 | EGA
GenomicsMolecular and Population Genetics (MPG) research at ICR DAC agreement
Data Access Committee EGAC00001000303
EGAC00001000303 | EGA
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