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ProteomicsThe Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi
We quantified the proteome of Dsc complex mutants (tul1gld1) and ESCRT mutants (vps4). Therefore we used stable isotope labeling with amino acids in cell culture (SILAC) to identify changes in the membrane proteome of tul1gld1orvps4 cells relative to WT cells or gld1 cells (labeled with “heavy” [13C...
ORGANISM(S): Candida albicans (Yeast) 
2025-05-07 | PXD055553 | Pride
Degron Dsc complex Quality control Escrt Golgi Lipids Ubiquitin 
UnknownYeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.
Not available
S-EPMC3083633 | biostudies-literature
UnknownThe Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi.
Not available
S-EPMC11513148 | biostudies-literature
UnknownSubunit architecture of the Golgi Dsc E3 ligase required for sterol regulatory element-binding protein (SREBP) cleavage in fission yeast.
Not available
S-EPMC3774371 | biostudies-literature
UnknownCurrent and potential applications of simultaneous DSC-FTIR microspectroscopy for pharmaceutical analysis.
Not available
S-EPMC9261823 | biostudies-literature
UnknownYeast sterol regulatory element-binding protein (SREBP) cleavage requires Cdc48 and Dsc5, a ubiquitin regulatory X domain-containing subunit of the Golgi Dsc E3 ligase.
Not available
S-EPMC3249121 | biostudies-literature
UnknownMonitoring of Pentoxifylline Thermal Behavior by Novel Simultaneous Laboratory Small and Wide X-Ray Scattering (SWAXS) and Differential Scanning Calorimetry (DSC).
Not available
S-EPMC4965141 | biostudies-literature
UnknownRevising Protein Corona Characterization and Combining ITC and Nano-DSC to Understand the Interaction of Proteins With Porous Nanoparticles.
Not available
S-EPMC8542777 | biostudies-literature
UnknownDsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast.
Not available
S-EPMC5625062 | biostudies-literature
TranscriptomicsNovel biomarkers for distributed stem cells: asymmetric self-renewal associated (ASRA) genes identification by combined cDNA micro-array orthogonal intersection and sparse feature analysis
Biomarkers unique for distributed stem cells (DSCs) have proven elusive. Previous searches for proteins expressed specifically in DSCs were hampered by difficulty obtaining pure DSCs and challenges to successfully mining complex molecular expression data. To identify novel candidates for DSC biomark...
ORGANISM(S): Mus musculus 
2014-06-30 | GSE40183 | GEO
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