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Tissue samples from human induced pluripotent stem cell-derived intestinal tissue (iPSC-derived intestinal progenitors seeded onto collagen hydrogels) which were transplanted subcutaneously in mice. Mice were sacrificed and tissues were collected after 2, 3 or 4 weeks following engraftment. The tiss...
ORGANISM(S): Homo sapiens 
CBFB-DSP-ChIPseq and YAP-DSP-ChIPseq
To further characterized the serrated pathway, we used the novel Digital Spatial Profiling (DSP) technology and its mRNA Cancer Transcriptome Atlas (CTA) panel, which includes over 1800 target gene, to investigate the underlying gene expression changes and pathways involved in sessile serrated lesio...
ORGANISM(S): Homo sapiens 
CRISPRi DSP-kd in iAT2
GeoMx DSP- profiling of mouse spleen
Intravenous immunoglobulin (IVIG) is a first-line drug prepared from human plasma for the treatment of autoimmune diseases (AID), especially immune thrombocytopenia (ITP). Since significant differences exist in protein types and expression levels between male and female plasma, and the prevalence of...
ORGANISM(S): Mus Musculus 
2023-09-26 | PXD045681 |
Discovery of traditional serrated adenoma by using DSP
The regulation of complex cellular activities in palmitate treated HepG2 cells, and the ensuing cytotoxic phenotype, involves cooperative interactions between genes. While previous approaches have largely focused on identifying individual target genes, elucidating interacting genes has thus far rema...
ORGANISM(S): Homo sapiens 
In order to identify cellular proteins interacting with the coat protein (CP) of Potato virus Y (PVY), we used coimmunoprecipitation of GFP-CP in PVY-infected Nicotiana benthamiana plants. To be able to pull down non-abundant interactors and to stabilize transient interactions, we used the crosslink...
ORGANISM(S): Nicotiana benthamiana ssRNA viruses 
2017-12-18 | PXD007836 | Pride
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