Sort   by:  
 Page size 
UnknownIntegrating artificial intelligence into lung cancer screening: a randomised controlled trial protocol.
Not available
S-EPMC10868245 | biostudies-literature
UnknownTenascin-C orchestrates radiotherapy-induced head and neck tumor regression
Not available
S-SCDT-10_1038-S44321-026-00406-8 | biostudies-other
UnknownTumor cells with neuronal intermediate progenitor features define a subgroup of 1p/19q co-deleted anaplastic gliomas.
Not available
S-EPMC8029323 | biostudies-literature
UnknownRole of Fas-associated death domain-containing protein (FADD) phosphorylation in regulating glucose homeostasis: from proteomic discovery to physiological validation.
Not available
S-EPMC3790283 | biostudies-literature
TranscriptomicsPromiscuous targeting of bromodomains by Bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia [set2]
Bromodomains (BRDs) have emerged as compelling targets for cancer therapy. The development of selective and potent BET inhibitors and their significant activity in diverse tumor models has rapidly translated into clinical studies and has motivated drug development efforts targeting non-BET BRDs. How...
ORGANISM(S): Homo sapiens 
2016-10-25 | E-GEOD-78829 | biostudies-arrayexpress
TranscriptomicsPromiscuous targeting of bromodomains by Bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia [set 1]
Bromodomains (BRDs) have emerged as compelling targets for cancer therapy. The development of selective and potent BET inhibitors and their significant activity in diverse tumor models has rapidly translated into clinical studies and has motivated drug development efforts targeting non-BET BRDs. How...
ORGANISM(S): Homo sapiens 
2016-10-25 | E-GEOD-78827 | biostudies-arrayexpress
TranscriptomicsConstitutively active Stat3 in mouse embryonic fibroblasts (MEFs)
Signal Transducer and Activator of Transcription 3 (STAT3) is considered as an oncogene being constitutively activated in a wide variety of primary human tumours, which often become addicted to its activity. Using primary fibroblasts derived from a knock-in mouse expressing only the constitutively a...
ORGANISM(S): Mus musculus 
2010-11-17 | E-GEOD-21507 | biostudies-arrayexpress
MetabolomicsProMetIS, deep phenotyping of mouse models by combined proteomics and metabolomics analysis

Genes are pleiotropic and getting a better knowledge of their function requires a comprehensive characterization of their mutants. Here, we generated multi-level data combining phenomic, proteomic and metabolomic acquisitions from plasma and liver tissues of two C57BL/6 N mouse models lacking the...

2021-09-01 | MTBLS1903 | MetaboLights
ProteomicsLkb1 suppresses amino acid-driven gluconeogenesis in the liver
Excessive glucose production in the liver is a key factor in the hyperglycemia observed in diabetes mellitus type 2. It is generally agreed to result from an increase in hepatic gluconeogenesis. Considerable attention has been devoted to the transcriptional regulation of key gluconeogenic enzymes, b...
ORGANISM(S): Mus musculus (Mouse) 
2020-12-01 | PXD019755 | Pride
Gluconeogenesis Phosphoproteome Sarcopenia Liver Cachexia Q-exactive Label-free quantification Amino acids Lkb1 Orbitrap fusion Refed mice 
ProteomicsLkb1 suppresses amino acid-driven gluconeogenesis in the liver
Excessive glucose production in the liver is a key factor in the hyperglycemia observed in diabetes mellitus type 2. It is generally agreed to result from an increase in hepatic gluconeogenesis. Considerable attention has been devoted to the transcriptional regulation of key gluconeogenic enzymes, b...
ORGANISM(S): Mus musculus (Mouse) 
2020-12-01 | PXD019757 | Pride
Gluconeogenesis Phosphoproteome Sarcopenia Liver Cachexia Q-exactive Label-free quantification Amino acids Lkb1 Orbitrap fusion 
Sort   by:  
 Page size