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MetabolomicsSupplementation of Bacillus sp. DU-106 reduces hypercholesterolemia and ameliorates gut dysbiosis in high-fat diet rats

Gut microbiota modulation by a probiotic is a novel therapy for hypercholesterolemia mitigation. This study initially investigated the potential hypocholesterolemic effect of Bacillus sp. DU-106 in hypercholesterolemic rats and explored its potential relation with gut microbiota. Sprague-Dawley r...

2021-04-08 | MTBLS1168 | MetaboLights
MetabolomicsMetabolomic assessment of acute cholestatic injuries induced by thioacetamide and by bile duct ligation, and the protective effects of Huang-Lian-Jie-Du-Decoction
Huang-Lian-Jie-Du-Decoction, a traditional Chinese formula, has been reported to protect liver from various injuries. Two cholestasis models of rats induced by thioacetamide and by bile duct ligation were established and treated with Huang-Lian-Jie-Du-Decoction. Nuclear Magnetic Resonance-based urin...
2016-06-08 | MTBLS149 | MetaboLights
MetabolomicsDifferential effects of Huang-Lian-Jie-Du Decoction on Alzheimer’s disease and normal rats

Introduction: Huang-Lian-Jie-Du Decoction (HLJDD), a botanical drug used in traditional medicine, has been used in the management of Alzheimer’s disease (AD). However, the mechanisms underlying its preventive effects remain inadequately understood, particularly due to the absence of metabolomic s...

2025-11-04 | MTBLS13256 | MetaboLights
TranscriptomicsHigh salt primes a specific activation state of macrophages, M(Na)
Purpose: Investigate effects of high salt on human macrophage activation Methods: Human monocytes-derived macrophages were treated by additional 51mM NaCl for 24 hours (NaCl groups) or not (Control groups). mRNA profiles were generated by RNA-Seq, in triplicate, using Ion proton（Life tech). qRT–PCR ...
ORGANISM(S): Homo sapiens 
2015-09-23 | E-GEOD-68482 | biostudies-arrayexpress
ProteomicsBlanc Du Bios Proteome - Proteome Profile of American Hybrid Grape cv
Blanc Du bois grapes are gaining popularity in the South eastern US due to its distinctive flavor and disease tolerance characteristics. Berry composition at harvest is a major contributing factor of wine quality. Blanc Du bois grapes are harvested from EL-38 and EL-39 stages depending on the style ...
ORGANISM(S): Vitis vinifera (Grape) 
2018-04-09 | PXD004157 | Pride
Lc-ms Grape Ripening 
TranscriptomicsExpression data from docetaxel-resistant prostate cancer cell lines
Docetaxel-based chemotherapy is the standard first-line therapy in metastatic castration-resistant prostate cancer. However, most patients eventually develop resistance to this treatment. The aim of the study was to identify key molecular genes and networks associated with docetaxel resistance in 2 ...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-GEOD-33455 | biostudies-arrayexpress
UnknownM(salen)-derived nitrogen-doped M/C (M = Fe, Co, Ni) porous nanocomposites for electrocatalytic oxygen reduction.
Not available
S-EPMC4034751 | biostudies-literature
UnknownNPM phosphorylation stimulates Cdk1, overrides G2/M checkpoint and increases leukemic blasts in mice.
Not available
S-EPMC2812569 | biostudies-literature
TranscriptomicsDNA methylation microarray comparison of blood cell DNA from Cri du chat patients to age- and sibling-matched controls
The goal of the experiment was to look for differences in DNA methylation for Cri du chat patients.
ORGANISM(S): Homo sapiens 
2022-10-22 | E-MTAB-12302 | biostudies-arrayexpress
TranscriptomicsA Multi-loop, Double-cube Microarray Design Applied to Prostate Cancer Cell Lines with Variable Sensitivity to Histone Deacetylase Inhibitors
Implementation of a complex design for a microarray experiment on resistance mechanisms of histone deacetylase inhibitors (HDACI). To improve our understanding of the underlying mechanism of HDACI resistance in prostate cancer cells, we designed a novel ‘‘multiple-loop, double-cube’’ cDNA microarray...
ORGANISM(S): Homo sapiens 
2011-12-17 | E-GEOD-34452 | biostudies-arrayexpress
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