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ProteomicsErk quantitative phosphorylation
To identify downstream phosphorylation substrates of Erk, we treated the iErk1; Erk KO cell line with and without doxycycline (DOX) for 48 hours. In the untreated group, intracellular Erk was found to be deficient. Mass spectrometry-based quantitative analysis was subsequently used to identify phosp...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-07 | PXD051508 | Pride
Mouse Erk 
ProteomicsCo-immunoprecipitation followed by mass spectrometry (Co-IP/MS) data of HNRNPF.
The interacting proteins of HNRNPF were identified in mouse embryonic stem cells by co-immunoprecipitation followed by mass spectrometry (Co-IP/MS).
ORGANISM(S): Mus musculus (Mouse) 
2025-06-30 | PXD065613 | Pride
Mesc Hnrnpf 
MetabolomicsSemen Cuscutae flavonoids activated the cAMP-PKA-CREB-BDNF pathway and exerted an antidepressant effect in mice

Background: Semen Cuscutae flavonoids (SCFs) constitute a class of metabolites of Semen Cuscutae, a botanical drug that was recently found to have an anti-depression effect. This study aimed to evaluate the anti-depression effects of SCFs in chronic unpredi...

2025-05-12 | MTBLS11688 | MetaboLights
ProteomicsComparative Proteomic Analysis of Fusobacterium nucleatum Clinical Isolates from Brain Abscess Patients versus the Standard Strain ATCC 25586
Comparative proteomic analysis of Fusobacterium nucleatum clinical strains isolated from brain abscess patients and the standard strain ATCC 25586, using label-free quantification (LFQ) to identify differentially expressed proteins and explore pathogenic mechanisms related to brain abscess.
ORGANISM(S): Fusobacterium Nucleatum Subsp. Nucleatum Atcc 25586 
2026-03-23 | PXD076046 |
ProteomicsIdentifying glycolysis in mitochondria as a new perspective on the pathogenesis of retinitis pigmentosa
The interaction proteins were obtained by immunoprecipitation (IP) of VWA8 using retinal pigment epithelium cell lysate.
ORGANISM(S): Homo Sapiens 
2026-03-29 | PXD076332 |
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