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ProteomicsProteomic analysis of linear ubiquitination substrates based on NAEK-Ub probe in live cells
While linear ubiquitin plays critical roles in multiple cell signaling pathways, few substrates have been identified. Global profiling of linear ubiquitin substrates represents a significant challenge because of the low endogenous level of linear ubiquitination, the none-specific binding of linear p...
ORGANISM(S): Homo Sapiens 
2022-02-11 | PXD031600 |
ProteomicsO-GlcNAcylation Promotes Cerebellum Development and Medulloblastoma Oncogenesis via SHH Signaling
Sonic hedgehog (Shh) signaling plays a critical role in regulating cerebellum development by maintaining the physiological proliferation of granule neuron precursors (GNPs), and its dysregulation leads to the oncogenesis of medulloblastoma. O-GlcNAcylation (O-GlcNAc) of proteins is an emerging regul...
ORGANISM(S): Homo Sapiens 
2022-06-02 | PXD034270 |
ProteomicsMass spectrometric profiling of intermolecular disulfide bonds between ROMO1 and its targets
Mass spectrometric profiling of intermolecular disulfide bonds between ROMO1 and its targets
ORGANISM(S): Homo Sapiens 
2024-06-11 | PXD053027 |
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