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GenomicsHansschlegelia quercus strain:Dub
Hansschlegelia quercus strain:Dub Genome sequencing and assembly
PRJNA523337 | ENA
TranscriptomicsChIP-chip of Drosophila Polycomb group proteins Asx and Calypso (PR-DUB) in larvae
Analysis of binding profile of the Polycomb group proteins Calypso and Asx (PR-DUB) in Drosophila melanogaster larvae.
ORGANISM(S): Drosophila melanogaster 
2010-05-03 | E-TABM-908 | biostudies-arrayexpress
ProteomicsElectrophile scanning by chemical prote-omics reveals a potent pan-active DUB probe for investigation of deubiquitinase activity in live cells
Deubiquitinases (DUBs) are proteases that hydrolyze isopeptide bonds linking ubiquitin to protein substrates, which can lead to reduced substrate degradation through the ubiquitin proteasome system. Deregulation of DUB activity has been im-plicated in many disease states, including cancer, neurodege...
ORGANISM(S): Homo sapiens (Human) 
2024-01-03 | PXD035417 | Pride
Ubiquitin-activity base probe Deubiquitinase Chemical probe Activity-based probe Electrophilic war-head Ubiquitin Dub Enzyme targeting Myc-deregulated cancer 
ProteomicsGlobal analysis of cancer cell responses to USP9X inhibition
Mass spectrometry-based 3X-FLAG-Ub-VS deubiquitinase (DUB) competition assay with cell extracts (DUB IP-MS) profiling MCF-7 cells with regard to specificity of WEHI-092, a selective inhibitor for USP9X. Sample key: #1-5 Untreated; #6-10 Ub-VS pre-treatment; #11-15 WEHI-092 treated (50 µM, 60 min).
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD074545 | Pride
GenomicsRNA sequencing of CRISPR/Cas9-generated A20 DUB-inative and A20 knock-out U937 cells to elucidate the role of human A20 DUB-domain
RNA sequencing of CRISPR/Cas9-generated A20 DUB-inative and A20 knock-out U937 cells to elucidate the role of human A20 DUB-domain
PRJNA480244 | ENA
GenomicsPR-DUB safeguards Polycomb repression through restricting H2AK119ub1 [ChIP-seq]
PR-DUB safeguards Polycomb repression through restricting H2AK119ub1 [ChIP-seq]
PRJNA773660 | ENA
GenomicsPR-DUB safeguards Polycomb repression through restricting H2AK119ub1 [RNA-seq]
PR-DUB safeguards Polycomb repression through restricting H2AK119ub1 [RNA-seq]
PRJNA773661 | ENA
TranscriptomicsRNA sequencing of CRISPR/Cas9-generated A20 DUB-inative and A20 knock-out U937 cells to elucidate the role of human A20 DUB-domain
Objectives: Genetic variations in TNFAIP3 (A20) de-ubiquitinase (DUB) domain increase the risk of systemic lupus erythematosus (SLE) and rheumatoid arthritis. A20 is a negative regulator of NF-κB but the role of its DUB domain and related genetic variants remain unclear. We aimed to study the functi...
ORGANISM(S): Homo sapiens 
2019-07-10 | GSE116780 | GEO
GenomicsMolecular mechanisms of the Asx C-terminal region for genomic targeting of PR-DUB in Drosophila
Molecular mechanisms of the Asx C-terminal region for genomic targeting of PR-DUB in Drosophila
PRJNA1489562 | ENA
UnknownProteomics-Based Identification of DUB Substrates Using Selective Inhibitors.
Not available
S-EPMC7855594 | biostudies-literature
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