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TranscriptomicsSystem responses to equal doses of photosynthetically usable radiation of blue, green, and red light in the marine diatom Phaeodactylum tricornutum.
We have studied the transcriptional, metabolic and photo-physiological responses to light of different spectral quality in the marine diatom Phaeodactylum tricornutum through time-series studies of cultures exposed to equal doses of photosynthetically usable radiation of blue, green and red light. T...
ORGANISM(S): Phaeodactylum tricornutum 
2014-12-22 | E-GEOD-55959 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Camplyobacter jejuni isolates from humans and chickens
This experiment compares C.jejuni isolates from humans and chicken. The samples were collected during a Swedish outbreak. The chicken samples were collected from groceries from the same geographical reagions as the infected humans. The genotypes of the C.jejuni isolates were compared using three dif...
ORGANISM(S): Campylobacter jejuni 
2008-04-08 | E-TABM-460 | biostudies-arrayexpress
GenomicsThe Demethylase JMJD2C/KDM4C Localizes to H3K4me3 Positive Transcription Start Sites (ChIP-seq KYSE150 cell line)
We have mapped binding sites for the histone demethylase, JMJD2C/KDM4C/GASC1, and the effect of JMJD2C depletion on H3K9me3 and H3K36me3 distributions in KYSE150 cells. The human esophageal carcinoma cell line, KYSE150, contains an amplification of the JMJD2C locus. ChIP-seq was performed using chr...
ORGANISM(S): Homo sapiens 
2014-01-09 | E-GEOD-53938 | biostudies-arrayexpress
GenomicsThe Demethylase JMJD2C/KDM4C Localizes to H3K4me3 Positive Transcription Start Sites (ChIP-seq MEFs)
We have mapped binding sites for the histone demethylase, Jmjd2c/Kdm4c/Gasc1, in mouse embryonic fibroblasts (MEFs) and the impact of Jmjd2c depletion on H3K9me3 and H3K36me3 distributions. ChIP-seq was performed using antibodies recognizing Jmjd2c, H3K9me3 or H3K36me3. Chromatin was obtained from c...
ORGANISM(S): Mus musculus 
2014-01-09 | E-GEOD-53939 | biostudies-arrayexpress
TranscriptomicsKnockout of the Acyl CoA binding protein (ACBP) in mice - expression profile from the liver of 21 days old ACBP-/- and +/+ mice.
The ACBP knockout were created by targeted disruption of the gene in mice. The expression profiling was performed on liver tissue from ACBP-/- (KO) and +/+ (WT) mice at the age of 21 days, which in our study is the time immediately before weaning. The mice used for this experiment were taken directl...
ORGANISM(S): Mus musculus 
2010-11-26 | E-GEOD-24451 | biostudies-arrayexpress
TranscriptomicsAn Integrated Analysis of Molecular Acclimation to High Light in the Marine Diatom Phaeodactylum tricornutum
Photosynthetic diatoms are exposed to rapid and unpredictable changes in irradiance and spectral quality, and must be able to adapt their light harvesting systems to varying light conditions. Molecular mechanisms behind light acclimation in diatoms are largely unknown. We set out to investigate the ...
ORGANISM(S): Phaeodactylum tricornutum 
2009-11-05 | E-GEOD-17237 | biostudies-arrayexpress
ProteomicsProteomic profiling of exosomes isolated from invasive and proliferative melanoma cell lines and correlation with exosomes from plasma of human melanoma patients pre- and post-checkpoint inhibitor treatment
Over the last decades, exosomes have received increasing attention due to their involvement in numerous pathologies including cancer. Tumor-derived exosomes and exosomes derived from the tumor microenvironment are implicated in multiple mechanisms that support disease progression such as the escape ...
ORGANISM(S): Homo sapiens (Human) 
2022-07-14 | PXD025475 | Pride
Lc-msms Cell culture Melanoma Plasma Exosomes 
UnknownCompound Heterozygous <i>RYR1</i> Variants in a Patient with Severe Congenital Myopathy: Case Report and Comparison with Additional Cases of Recessive <i>RYR1</i>-Related Myopathy.
Not available
S-EPMC11477233 | biostudies-literature
ModelsCellière2011 - Plasticity of TGF-β Signalling
Cellière2011 - Plasticity of TGF-β Signalling Transforming growth factor beta (TGF-β) signalling has been implicated as an important regulator of almost all major cell behaviours, including proliferation, differentiation, cell death, and motility. It remains unclear that how the T...
2024-09-02 | BIOMD0000000600 | BioModels
TranscriptomicsNSCLC cells treated with Gefitinib
About 10% of all NSCLC patients respond to gefitnib treatment and all of these patients will acquire resistance to the EGFR TKI. We used microarray to look at global gene expression changes in untreated cells vs gefitinib treated cells to identify key characters for the acquisition of resistance. NS...
ORGANISM(S): Homo sapiens 
2011-01-27 | E-GEOD-23206 | biostudies-arrayexpress
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