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TranscriptomicsA Novel Tumor suppressor network in squamous malignancies
The specific ablation of Rb1 gene in stratified epithelia (RbF/F;K14cre) promotes proliferation and altered differentiation but is insufficient to produce spontaneous tumors. The pRb relative, p107, compensates some of the functions of pRb in these tissues, however RbF/F;K14cre;p107-/- mice die post...
ORGANISM(S): Mus musculus 
2012-12-21 | E-GEOD-38257 | biostudies-arrayexpress
TranscriptomicsIn vivo disruption of Rb-E2F-Ezh2 signaling loop causes bladder cancer development
Bladder cancer (BC) is a highly prevalent human disease in which Rb pathway inactivation and epigenetic alterations are common events. However, the connection between these two processes is still poorly understood. Here we show that the in vivo inactivation of all Rb family genes in the mouse urothe...
ORGANISM(S): Homo sapiens 
2014-10-02 | E-GEOD-38264 | biostudies-arrayexpress
TranscriptomicsExpression data from Arabidopsis thaliana treated with NO donor SNP, compared to NO depletion by cPTIO
Nitric oxide (NO) is considered a key regulator of plant developmental processes and defense. Characterization of root-related phenotypes and the involvement of NO in the regulation of primary root growth. Three-experimental condition, SDW, SNP and cPTIO. Biological replicates: 3 control replicates ...
ORGANISM(S): Arabidopsis thaliana 
2015-12-21 | E-GEOD-21556 | biostudies-arrayexpress
UnknownDiverse Large HIV-1 Non-subtype B Clusters Are Spreading Among Men Who Have Sex With Men in Spain.
Not available
S-EPMC6457325 | biostudies-literature
UnknownFungal Planet description sheets: 469-557.
Not available
S-EPMC5315290 | biostudies-literature
UnknownFungal Planet description sheets: 400-468.
Not available
S-EPMC4988374 | biostudies-literature
UnknownLong-Term Real-World Effectiveness and Safety of Ustekinumab in Crohn's Disease Patients: The SUSTAIN Study.
Not available
S-EPMC9629456 | biostudies-literature
UnknownChildren living with HIV in Europe: do migrants have worse treatment outcomes?
Not available
S-EPMC9293243 | biostudies-literature
UnknownAdjuvant Olaparib for Patients with <i>BRCA1</i>- or <i>BRCA2</i>-Mutated Breast Cancer.
Not available
S-EPMC9126186 | biostudies-literature
UnknownAge-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality.
Not available
S-EPMC8631592 | biostudies-literature
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