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ProteomicsDUSP2 dephosphorylates STAT3 at Y705 and S727 residues
In the related study, to determine whether DUSP2 definitively served as a phosphatase for STAT3, an in vitro phosphatase assay was used. Using S-tag beads, p-STAT3 was pulled down from IL-6 stimulated HEK293T cells transfected with STAT3-S-Tag. DUSP2 or control protein, which was purified from HEK29...
ORGANISM(S): Homo sapiens (Human) 
2015-10-13 | PXD002743 | Pride
Dusp2 Phosphorylation Stat3 
GenomicsRNAseq DUSP2-KO/WT Jurkat cells
The dual specificity phosphatase 2 (DUSP2) act as distal regulatory node in T Cell signaling
PRJEB105387 | ENA
TranscriptomicsHeLa cell: DUSP2 overexpression vs. control
The MAPK-specific phosphatase, dual-specificity phosphatase-2 (DUSP2), was negatively regulated by HIF-1a under hypoxia. To identify the downstream genes regulated by DUSP2, microarray analysis was performed. Agilent two color microarray was used to examine the molecular profile after DUSP2 overexpr...
ORGANISM(S): Homo sapiens 
2015-09-30 | GSE66656 | GEO
GenomicsDUSP2 Suppresses the Chromatin Remodeling BAF Complex to Orchestrate CD8+ T Cell Effector Programming
DUSP2 Suppresses the Chromatin Remodeling BAF Complex to Orchestrate CD8+ T Cell Effector Programming
PRJNA1369182 | ENA
UnknownRegulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2.
Not available
S-EPMC5333157 | biostudies-literature
UnknownDUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination.
Not available
S-EPMC7170376 | biostudies-literature
UnknownDUSP2-mediated inhibition of tubular epithelial cell pyroptosis confers nephroprotection in acute kidney injury.
Not available
S-EPMC9274747 | biostudies-literature
GenomicsDUSP2 Suppresses the Chromatin Remodeling BAF Complex to Orchestrate CD8+ T Cell Effector Programming [ChIP-Seq]
DUSP2 Suppresses the Chromatin Remodeling BAF Complex to Orchestrate CD8+ T Cell Effector Programming [ChIP-Seq]
PRJNA1365065 | ENA
GenomicsDUSP2 Suppresses the Chromatin Remodeling BAF Complex to Orchestrate CD8+ T Cell Effector Programming [ATAC-seq]
DUSP2 Suppresses the Chromatin Remodeling BAF Complex to Orchestrate CD8+ T Cell Effector Programming [ATAC-seq]
PRJNA1367577 | ENA
GenomicsDUSP2 Suppresses the Chromatin Remodeling BAF Complex to Orchestrate CD8+ T Cell Effector Programming [RNA-seq]
DUSP2 Suppresses the Chromatin Remodeling BAF Complex to Orchestrate CD8+ T Cell Effector Programming [RNA-seq]
PRJNA1365061 | ENA
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