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TranscriptomicsTechnical Analysis of Fundulus heteroclitus cDNA Microarrays, experiment A
In the teleost fish Fundulus heteroclitus there is extensive variation in gene expression among individuals within and between populations. Accurate measures of the variation in mRNA expression using microarrays can be confounded by technical variation, which includes variation in RNA isolation pro...
ORGANISM(S): Fundulus heteroclitus 
2010-05-15 | E-GEOD-12858 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Sinorhizobium meliloti after exposure to elevated concentrations of the heavy metals cadmium and zinc to analyze stress responses
The stress response of the soil bacterium Sinorhizobium meliloti towards elevated concentrations of the heavy metals cadmium and zinc was analyzed via transcriptional profiling.
ORGANISM(S): Sinorhizobium meliloti 
2008-03-15 | E-MTAB-13 | biostudies-arrayexpress
TranscriptomicsWide-genome analysis of hepatocytes isolated from male and female rats treated with glucocorticoid.
Glucocorticoids are widely used therapeutically to suppress inflammatory/immune responses and most of their effects are produced either by altering transcription of specific genes directly, or by altering the expression of transcription factors that subsequently alter the expression of downstream ge...
ORGANISM(S): Rattus norvegicus 
2010-10-30 | E-GEOD-24255 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of strains of Leishmania infantum, Leishmania major and Leishmania tarentolae
The genomic DNAs of strains JPCM5 and 263 of L. infantum, strains LV39 and Friedlin of L. major and strains Parrot-TarII and S125 of L. tarentolae were used in comparative genomic hybridizations to reveal the intra-species and inter-species gene content, and to validate L. tarentolae Parrot-TarII ge...
ORGANISM(S): Leishmania tarentolae 
2011-10-20 | E-GEOD-27184 | biostudies-arrayexpress
TranscriptomicsTimEX from human embryonic stem cells, mesenchymal stem cells, and erythroid cells
The organization of mammalian DNA replication is poorly understood. We have produced genome-wide high-resolution dynamic maps of the timing of replication in human erythroid, mesenchymal and embryonic stem cells using TimEX, a method that relies on gaussian convolution of massive, highly redundant d...
ORGANISM(S): Homo sapiens 
2009-11-04 | E-GEOD-18679 | biostudies-arrayexpress
TranscriptomicsRecurrent breakpoint genes in colorectal cancer
In this study our aim was to document recurrent DNA copy number aberration associated breakpoints in primary tumors of colorectal cancer patients that ultimately received systemic treatment in the context of metastatic disease. Such data can be used to catalogue copy number aberration associated bre...
ORGANISM(S): Homo sapiens 
2014-11-14 | E-GEOD-63216 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of dendritic cells derived from the bone marrow of wild type and Lmp7-/-Mecl1-/- mice
Comparison of the MHC I peptidome and of the transcriptome of dendritic cells derived from WT and Lmp7-/-Mecl1-/- mice bone marrow
ORGANISM(S): Mus musculus 
2010-07-22 | E-TABM-750 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Saccharomyces cerevisiae pGAL1-MKS1, pGAL1-NNK1, and pGAL1-FMP48 overexpression
Analysis of the transcriptional effects of pGAL1-MKS1, pGAL1-NNK1, and pGAL1-FMP48 overexpression. BY4700 gal1::NAT ura3delta0 S. cerevisiae cells carrying a [pGAL1-MKS1-HA, URA3, CEN], [pGAL1-NNK1-HA, URA3, CEN], or [pGAL1-FMP48-HA, URA3, CEN] plasmid, or empty vector BG1805, were grown to early lo...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-25 | E-MEXP-2171 | biostudies-arrayexpress
TranscriptomicsWhole Adult Organism Transcriptional Profiling of Metal Exposures in Zebrafish
A convergence of technological breakthroughs in the past decade has facilitated the development of rapid screening tools for biomarkers of toxicant exposure and effect. Platforms using the whole adult organism to evaluate the genome-wide response to toxicants are especially attractive. Recent work d...
ORGANISM(S): Danio rerio 
2014-06-10 | E-GEOD-50648 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human squamous cell carcinomas to predict response to neoadjuvant chemoradiotherapy in oesophageal cancer patients
To use gene expression profiles to predict response to neoadjuvant chemoradiotherapy in oesophageal cancer patients.
ORGANISM(S): Homo sapiens 
2008-02-08 | E-MEXP-426 | biostudies-arrayexpress
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