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TranscriptomicsTranscriptomic responses of Atlantic salmon (Salmo salar) to environmental enrichment during juvenile rearing
Captive rearing programs (hatcheries) are often used in conservation and management efforts for at-risk salmonid fish populations. However, hatcheries typically rear juveniles in environments that contrast starkly with natural conditions, which may lead to phenotypic and/or genetic changes that adve...
ORGANISM(S): Salmo salar 
2014-12-10 | E-GEOD-63982 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling using microarrays to elucidate the effects of partial whiB1 gene deletion in Mycobacterium tuberculosis H37Rv
DNA microarray analysis was performed on RNA from a strain of Mycobacterium tuberculosis H37Rv in which the essential whiB1 gene was deleted from the chromosome but partially complemented by a wild type allele on a plasmid, compared to RNA from H37Rv wild type containing the same plasmid.
ORGANISM(S): Mycobacterium tuberculosis 
2017-12-22 | E-MTAB-5814 | biostudies-arrayexpress
TranscriptomicsDrosophila Sex Hierarchy Regulated Gene Expression in 48 hour APF Pupae
Drosophila melanogaster undergoes a complete metamorphosis, during which time the larval male and female forms transition into sexually dimorphic, reproductive adult forms. To understand this complex morphogenetic process at a molecular-genetic level, we performed whole genome microarray analyses. ...
ORGANISM(S): Drosophila melanogaster 
2009-02-10 | E-GEOD-11311 | biostudies-arrayexpress
TranscriptomicsMicroarray study of the Sex Inducer Proteins in Cryptococcus neoformans var. neoformans (JEC20/21)
To identify genes regulated by the homeodomain transcription factors Sxi1M-NM-1 and Sxi2a (Sex Inducer 1M-NM-1 and 2a) in Cryptococcus neoformans, we carried out a whole-genome expression experiment. We performed two independent whole-genome microarray experiments comparing transcript levels in cell...
ORGANISM(S): Cryptococcus neoformans var. neoformans 
2014-07-01 | E-GEOD-57287 | biostudies-arrayexpress
TranscriptomicsClinically Relevant Copy Number Variations Detected in Cerebral Palsy
Cerebral palsy (CP) represents a group of non-progressive clinically heterogeneous disorders that are characterized by motor impairment and early age-of-onset, frequently accompanied by co-morbidities. The cause of CP has historically been attributed to environmental stressors resulting in brain dam...
ORGANISM(S): Homo sapiens 
2015-07-28 | E-GEOD-70374 | biostudies-arrayexpress
TranscriptomicsTranscriptomics adaptation of porcine adipose- and bone marrow-derived stem cells during adipogenic and osteogenic differentiation
Adipose-derived and bone-marrow-derived mesenchymal stem cells were collected from 3 pigs and cultivated in vitro up to 3 passages. At passage 3 cells were cultured to 80% confluence and induced to differentiate in adipose and bone. Cell were harvested at 0 day of differentiation (dd) or pre-differe...
ORGANISM(S): Sus scrofa 
2012-03-01 | E-GEOD-25854 | biostudies-arrayexpress
TranscriptomicsMapping of cohesion factor association sites in S. cerevisiae - Meiosis I chromosome segregation is established through regulation of microtubule-kinetochore interactions.
During meiosis, a single round of DNA replication is followed by two consecutive rounds of nuclear divisions called meiosis I and meiosis II. In meiosis I, homologous chromosomes segregate, while sister chromatids remain together. Determining how this unusual chromosome segregation behavior is estab...
ORGANISM(S): Saccharomyces cerevisiae 
2012-10-05 | E-GEOD-41339 | biostudies-arrayexpress
TranscriptomicsDNA methylation in Arabidopsis thaliana
DNA methylation in wild type bolting plants, wild type seedlings, and ddm1 seedlings. The purpose of the McrBC methylation microarray assay is to determine which regions of a genome are methylated versus those that are unmethylated in a single Arabidopsis thanliana genotype. McrBC is a methylation-s...
ORGANISM(S): Arabidopsis thaliana 
2010-06-09 | E-GEOD-1355 | biostudies-arrayexpress
TranscriptomicsFRUM and EcR-regulated expression during Drosophila development
In Drosophila, male-specific FRU (FRUM) is required to establish the potential for courtship behaviors, but the downstream effectors of FRUM during development are largely unknown. A microarray-based approach identified genes that are differentially expressed as a consequence of FRUM in pupae, in b...
ORGANISM(S): Drosophila melanogaster 
2009-09-21 | E-GEOD-11752 | biostudies-arrayexpress
TranscriptomicsInhibition of endogenous MTF-1 signaling in zebrafish embryos identifies novel roles for MTF-1 in development
The MTF-1 transcription factor is considered to be a master regulator of zinc homoestasis. We previously characterized a constitutively nuclear, dominant-negative zebrafish MTF-1/eGFP fusion protein (dnMTF-1). In this study, in vitro transcribed dnMTF-1 mRNA was microinjected into zebrafish embryos ...
ORGANISM(S): Danio rerio 
2014-04-25 | E-GEOD-51298 | biostudies-arrayexpress
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