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MetabolomicsIdentifying metabolic alterations associated with coral growth anomalies using 1H NMR metabolomics
Coral growth anomalies (GAs) are tumor-like protrusions that are detrimental to coral health, impacting both the coral skeleton and soft tissues. These lesions are increasingly found throughout the tropics and are commonly associated with high human population density, yet little is known about the ...
2021-06-15 | MTBLS2424 | MetaboLights
MetabolomicsSpatial metabolomics shows contrasting phosphonolipid distributions in tissues of marine bivalves

Lipids are an integral part of cellular membranes, vary between species, and allow cells to alter stiffness, permeability and curvature. Among lipids, phosphonolipids uniquely contain a phosphonate bond between carbon and phosphorous. Despite this distinctive biochemical characteristic, few model...

2022-06-26 | MTBLS2960 | MetaboLights
MetabolomicsMetabolic Dynamics of In Vitro CD8+ T Cell Activation

CD8+ T cells detect and kill virally infected or cancerous cells. When activated from their naïve state, T cells undergo a complex transition, including major metabolic reprogramming. Detailed resolution of metabolic dynamics of a wide range of metabolites is needed to advance the field of immuno...

2021-06-02 | MTBLS2145 | MetaboLights
MetabolomicsClock regulation of metabolites reveals coupling between transcription and metabolism
The circadian clock is intricately connected with metabolism, however the precise details of these connections are incomplete. Here we used high temporal resolution metabolite profiling to determine circadian regulation of mouse liver and cell autonomous metabolism. In mouse liver, we found ~50% of ...
2017-04-05 | MTBLS292 | MetaboLights
UnknownPrimula vulgaris (primrose) genome assembly, annotation and gene expression, with comparative genomics on the heterostyly supergene.
Not available
S-EPMC6299000 | biostudies-literature
TranscriptomicsINTEGRATIVE ONCOGENOMIC AND HIGH-THROUGHPUT SEQUENCING ANALYSES OF THE COMMONLY DELETED REGION IN CHROMOSOME 7q32 IN SPLENIC MARGINAL ZONE LYMPHOMA (CGH)
Using high-resolution genomic microarray analysis, a distinct genomic profile was defined in 114 samples from patients with splenic marginal zone lymphoma (SMZL). Notably, deletion or uniparental disomy of chromosome 7q were detected in 39% of SMZLs but in only 9 of 170 (5%) mature B-cell lymphomas ...
ORGANISM(S): Homo sapiens 
2012-07-31 | E-GEOD-35367 | biostudies-arrayexpress
UnknownAn updated nomenclature for keratin-associated proteins (KAPs).
Not available
S-EPMC3269608 | biostudies-literature
ProteomicsElucidating the Cellular Machinery for Lipid Storage in Plants
The overarching goal of this project is to understand the underlying mechanism for packaging storage lipids into lipid droplets in plant cells. Our group has identified several proteins involved in plant lipid droplet formation, but the inventory of proteins participating in this cellular process is...
ORGANISM(S): Nicotiana benthamiana 
2022-02-16 | PXD023043 | Pride
Lipid droplet Neutral lipids Seipin Endoplasmic reticulum Ldip 
UnknownTranscriptional profiling and network analysis of the murine angiotensin II-induced abdominal aortic aneurysm.
Not available
S-EPMC3180735 | biostudies-literature
ProteomicsArabidopsis LDIP is an LDAP-interacting protein that influences lipid droplet biogenesis and neutral lipid homeostasis in both leaves and seeds
Cytoplasmic lipid droplets (LDs) are found in all types of plant cells where they are derived from the endoplasmic reticulum (ER) and function as a repository for neutral lipids, as well as serving in lipid remodelling and signalling. However, the mechanisms underlying the formation and functioning ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2017-11-06 | PXD007192 | Pride
Arabidopsis thaliana Biogenesis Ldap Neutral lipids Endoplasmic reticulum Ldip Lipid droplet Protein targeting 
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