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ProteomicsDynamic study of the cell wall integrity signaling pathway in Aspergillus nidulans
A phosphoproteomic evaluation of the cellular response to micafungin (cell wall perturbant) in the filamentous fungi, A. nidulans, reveals putative, currently unknown cell wall integrity signaling (CWIS) associated proteins. This study used thirteen timepoints were taken from 0 to 10 minutes after c...
ORGANISM(S): Emericella nidulans (Aspergillus nidulans) 
2020-07-16 | PXD015038 | Pride
Cell wall integrity signaling Dynamic Lfq Aspergillus nidulans Micafungin Phosphoproteomics 
UnknownDynamic Transcriptomic and Phosphoproteomic Analysis During Cell Wall Stress in Aspergillus nidulans.
Not available
S-EPMC8014999 | biostudies-literature
ProteomicsDynamic phosphoproteomic profiling of quiescence entry and exit in MDA-MB-231 cells
Quiescent cancer cells (QCCs) evade conventional therapies and contribute to minimal residual disease (MRD) and relapse, yet the signaling pathways governing their survival remain poorly understood. Here, we performed integrative proteomic and phosphoproteomic profiling of triple-negative breast can...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD071322 | Pride
Human Breast cancer Quiescence Cell cycle Phosphorylation 
ProteomicsIntegrative analysis of proteomic and phosphoproteomic of granulosa cells during follicular atresia in porcine
Ovarian follicular atresia is a natural physiological process, but its mechanism is not fully understood. In this study, a quantitative proteomic and phosphoproteomic of granulosa cell (GC) in the healthy (H), slightly atretic (SA), and atretic follicles (A) of porcine were performed by TMT labeling...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-09-09 | PXD020899 | Pride
Porcine  follicular atresia  granulosa cell  proteomic  phosphoproteomic 
ProteomicsOrganising the cell cycle in the absence transcriptional control: Dynamic phosphorylation co-ordinates the Trypanosoma brucei cell cycle post-transcriptionally
The cell division cycle of the unicellular eukaryote Trypanosome brucei is tightly regulated despite the paucity of transcriptional control that results from the arrangement of genes in polycistronic units and lack of dynamically regulated transcription factors. To identify the contribution of dynam...
ORGANISM(S): Trypanosoma brucei 
2019-10-22 | PXD013488 | Pride
Trypanosoma brucei Phosphoproteomics Cell cycle Silac 
UnknownSynthesizing Signaling Pathways from Temporal Phosphoproteomic Data.
Not available
S-EPMC6295338 | biostudies-literature
ProteomicsPhosphoproteomic Analysis Defines BABAM1 as mTORC2 Downstream Effector Promoting DNA Damage Response in Glioblastoma Cells
Glioblastoma (GBM) is a devastating primary brain cancer with a poor prognosis. GBM is associated with an abnormal mechanistic target of rapamycin (mTOR) signaling pathway, consisting of two distinct kinase complexes: mTORC1 and mTORC2. The complexes play critical roles in cell proliferation, surviv...
ORGANISM(S): Homo sapiens (Human) 
2022-11-08 | PXD033325 | Pride
Phosphoproteomics Mtorc2 Glioblastoma Babam1 Dna damage 
ProteomicsDynamic phosphoprotemics yeast nitrogen up-shift
To resolve the temporal sequence of phosphorylation events responding to nutritional and chemically induced up and downshifts of TORC1 signaling in S. cerevisiae wildtype, we performed quantitative MS phosphoproteomics upon nitrogen-quality up and downshifts and rapamycin treatment. We generated a h...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-02-22 | PXD000911 | Pride
Proline Dynamic phosphoproteomic Glutamine Yeast Nitrogen upshift 
ProteomicsA dynamic phosphoproteomic analysis provides a comprehensive understanding of the C4 plant maize response to natural diurnal changes
As sessile organisms, plants have to respond to rapid changes in numerous environmental factors, mainly the diurnal changes of light, temperature, and humidity. Maize is the world’s most grown crop, and as a C4 plant it exhibits high photosynthesis capacity and stress resistance than C3 plants. Reve...
ORGANISM(S): Zea Mays 
PXD036545 |
ProteomicsQuantitative Proteomic and Phosphoproteomic profilings of two foxtail millet cultivars under salinity
In this project, comprehensive proteomic and phosphoproteomic analysis was performed to explore sophisticated responsive networks of foxtail millet varieties of An04 and Yugu2 under salinity. Isobaric tags for relative and absolute quantitation-based (iTRAQ) and tandem mass tags-based (TMTs) quantit...
ORGANISM(S): Setaria italica 
2022-02-17 | PXD025969 | Pride
Foxtail millet (setaria italica)  salt stress  proteomic and phosphoproteomic  phosphorylation  lc-ms/ms 
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